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CAS RN: 137-58-6 | Product Number: L0156

Lidocaine


Purity: >99.0%(T)(HPLC)
Synonyms:
  • 2-Diethylamino-N-(2,6-dimethylphenyl)acetamide
Documents:
25G
£33.00
4   ≥20 
100G
£83.00
2   ≥20 
500G
£265.00
1   ≥20 

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Product Number L0156
Purity / Analysis Method >99.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__4H__2__2N__2O = 234.34  
Physical State (20 deg.C) Solid
Store Under Inert Gas Store under inert gas
Condition to Avoid Air Sensitive
CAS RN 137-58-6
Reaxys Registry Number 2215784
PubChem Substance ID 87572107
SDBS (AIST Spectral DB) 27423
Merck Index (14) 5482
MDL Number

MFCD00026733

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 99.0 area%
Purity(Nonaqueous Titration) min. 99.0 %
Melting point 66.0 to 70.0 °C
Solubility in Methanol almost transparency
Properties (reference)
Melting Point 69 °C
Boiling Point 182 °C/4 mmHg
Solubility in water Insoluble
Degree of solubility in water 410 mg/l   30 °C
Solubility (soluble in) Alcohol,Chloroform,Ether,Benzene
GHS
Pictogram Pictogram Pictogram
Signal Word Danger
Hazard Statements H302 : Harmful if swallowed.
H362 : May cause harm to breast-fed children.
H370 : Causes damage to organs.
H372 : Causes damage to organs through prolonged or repeated exposure.
H317 : May cause an allergic skin reaction.
Precautionary Statements P263 : Avoid contact during pregnancy and while nursing.
P260 : Do not breathe dust/ fume/ gas/ mist/ vapours/ spray.
P201 : Obtain special instructions before use.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves.
P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor.
Related Laws:
EC Number 205-302-8
RTECS# AN7525000
Transport Information:
HS Number 2924297099
Application
Lidocaine: A Voltage Gated Sodium Channel Blocker

Lidocaine is widely used for regional anesthesia and postoperative pain relief, and these effects involve the blockade of voltage-dependent sodium channels which play a key role in the pathogenesis of neuropathic pain. Thus, lidocaine stabilizes the neuronal cell membrane by inhibiting the movement of sodium ions into a nerve cell. Lignocaine is also a class IB antiarrhythmic agent as a sodium channel blocker. Lidocaine is metabolized rapidly by CYP1A2 and CYP3A4 in liver to main active metabolites, monoethylglycine xylidide (MEGX) [N1171] and glycinexylidide (GX) [G0579]. (The product is for research purpose only.)

References


PubMed Literature


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