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Published TCIMAIL newest issue No.199
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CAS RN: 13010-47-4 | Product Number: L0251
Lomustine
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Purity: >98.0%(HPLC)(qNMR)
Synonyms:
- 1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 50MG |
£27.00
|
5 | ≥80 |
|
|
| 200MG |
£84.00
|
4 | 34 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | L0251 |
Purity / Analysis Method 
|
>98.0%(HPLC)(qNMR) |
| Molecular Formula / Molecular Weight | C__9H__1__6ClN__3O__2 = 233.70 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Frozen (<0°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container
|
200MG-Glass Bottle with Plastic Insert (View image), 50MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 13010-47-4 |
| Reaxys Registry Number | 2125058 |
| PubChem Substance ID | 160871478 |
| Merck Index (14) | 5564 |
| MDL Number | MFCD00012392 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(qNMR) | min. 98.0 % |
| Melting point | 89.0 to 93.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 91 °C |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. H360 : May damage fertility or the unborn child. H371 : May cause damage to organs. H370 : Causes damage to organs. H372 : Causes damage to organs through prolonged or repeated exposure. H373 : May cause damage to organs through prolonged or repeated exposure. H340 : May cause genetic defects. H350 : May cause cancer. |
| Precautionary Statements | P260 : Do not breathe dust. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. |
Related Laws:
| EC Number | 235-859-2 |
| RTECS# | YS4900000 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | III |
| HS Number | 2929909090 |
Application
Studies on the Antitumor Activity of Lomustine
References
- Depletion of mammalian O6-alkylguanine-DNA alkyltransferase activity by O6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents
- A gene expression database for the molecular pharmacology of cancer
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