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CAS RN: 2216-51-5 | Product Number: M0545

(-)-Menthol


Purity: >99.0%(GC)
Synonyms:
  • (-)-p-Menthan-3-ol
Documents:
25G
£14.00
5   ≥20 
100G
£30.00
4   16  
500G
£86.00
2   19  

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Product Number M0545
Purity / Analysis Method >99.0%(GC)
Molecular Formula / Molecular Weight C__1__0H__2__0O = 156.27  
Physical State (20 deg.C) Solid
CAS RN 2216-51-5
Reaxys Registry Number 1902293
PubChem Substance ID 87572580
SDBS (AIST Spectral DB) 2543
Merck Index (14) 5837
MDL Number

MFCD00062979

Specifications
Appearance White or Colorless powder to crystal
Purity(GC) min. 99.0 %
Optical purity(GC) min. 99.0 ee%
Melting point 42.0 to 45.0 °C
Properties (reference)
Melting Point 43 °C
Boiling Point 216 °C
Specific Rotation -50° (C=10,EtOH)
Solubility in water Insoluble
Degree of solubility in water 490 mg/l   25 °C
Solubility (very soluble in) Ether,Methanol
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
H336 : May cause drowsiness or dizziness.
Precautionary Statements P261 : Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ eye protection/ face protection.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P304 + P340 + P312 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell.
P403 + P233 : Store in a well-ventilated place. Keep container tightly closed.
Related Laws:
EC Number 218-690-9
RTECS# OT0700000
Transport Information:
HS Number 2906110000
Application
(-)-Menthol: A Monocyclic Monoterpene Alcohol exhibiting Many Bioactivities

(±)-Menthol [M0321] is a monocyclic monoterpene alcohol found in peppermint which is known to exhibit biological activity such as antibacterial, antifungal, antipruritic, anticancer and analgesic effects. (±)-Menthol is widely used as a product in cosmetics, a flavoring agent, and a synthetic intermediate. (±)-Menthol is a racemic mixture of the (-)-menthol and (+)-menthol [M3170]. (-)-Menthol is more common than (+)-menthol in nature, and exhibits, antibacterial, anticancer, and analgesic properties, as well as inhibits cholinesterase. In contrast, (+)-menthol has antifungal activity, but does not exhibit antibacterial, anticancer, analgesic properties, or cholinesterase inhibitory activities.1) It has been reported that menthol's characteristic pleasant cooling sensation is due to the activation of sensory neurons generally termed transient receptor potential (TRP) channels, in particular transient receptor potential melastatin family member 8 (TRPM8) and transient receptor potential subfamily ankyrin 1 channel (TRPA1).2-4) (The product is for research purpose only.)

References


PubMed Literature


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