text.skipToContent text.skipToNavigation

Maximum quantity allowed is 999

Please select the quantity

CAS RN: 133407-82-6 | Product Number: M3244

MG-132


Purity: >95.0%(qNMR)
Synonyms:
  • Cbz-Leu-Leu-Leu-CHO
  • Carbobenzoxy-L-leucyl-L-leucyl-L-leucinal
  • Benzyl [(S)-4-Methyl-1-[[(S)-4-methyl-1-[[(S)-4-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]carbamate
Documents:
10MG
£96.00
Contact Us 3  

*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).


Product Number M3244
Purity / Analysis Method >95.0%(qNMR)
Molecular Formula / Molecular Weight C__2__6H__4__1N__3O__5 = 475.63 
Physical State (20 deg.C) Solid
Storage Temperature Frozen (-20°C)
Store Under Inert Gas Store under inert gas
Condition to Avoid Air Sensitive,Heat Sensitive
CAS RN 133407-82-6
Reaxys Registry Number 7668447
MDL Number

MFCD00674886

Specifications
Appearance White to Light yellow powder to crystal
Purity(qNMR) min. 95.0 %
NMR confirm to structure
Properties (reference)
Melting Point 84 °C
GHS
Related Laws:
RTECS# OH2824610
Transport Information:
HS Number 2924297099
Application
MG-132: A Tripeptide Aldehyde Proteasome Inhibitor

Proteasomes are protein complexes which degrade unneeded or damaged proteins by proteolysis. MG-132 (carbobenzyl-Leu-Leu-Leu-aldehyde) is the first developed tripeptide aldehyde proteasome inhibitor derived from a Chinese medicinal plant. Similarly to bortezomib [B5741], MG-132 inhibits the chymotrypsin-like proteolytic (β5) site of the 26S proteasome. MG-132 enhances cytostatic/cytotoxic effects of chemo- and radiotherapy, and increases apoptosis induced by other agents. (The product is for research purpose only.)

References


Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.

The requested SDS is not available.

Please Contact Us for more information.

Specifications
C of A & Other Certificates
Please enter Lot Number Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Analytical Charts
Please enter Lot Number Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.

The requested analytical chart is not available. Sorry for the inconvenience.

Other Documents

Session Status
Your session will timeout in 10 minutes. You will be redirected to the HOME page after session timeout. Please click the button to continue session from the same page. minute. You will be redirected to the HOME page after session timeout. Please click the button to continue session from the same page.

Your session has timed out. You will be redirected to the HOME page.