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CAS RN: 159989-65-8 | Product Number: N0986

Nelfinavir Mesylate


Purity: >97.0%(HPLC)
Synonyms:
  • Nelfinavir Methanesulfonate
Documents:
25MG
£106.00
1   8  
100MG
£292.00
2   31  

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Note:

Previously this product had been labeled as a hydrate form both in product name and molecular formula. The hydrate form had no exclusive CAS RN and used to share the same CAS RN as the anhydrous form.
To avoid any misleading information and since moisture in product is considered as an impurity, we have decided to remove the term 'Hydrate' from product name and 'xH2O' from the molecular formula for such products.
Please use it at ease since there is no difference in product quality, even if you see the previous indications on a part of label.

This product is a sample for RUO (research use only). Do not use this product for any purpose other than testing and research.

Product Number N0986
Purity / Analysis Method >97.0%(HPLC)
Molecular Formula / Molecular Weight C__3__2H__4__5N__3O__4S·CH__4O__3S = 663.89 
Physical State (20 deg.C) Solid
Storage Temperature Refrigerated (0-10°C)
Store Under Inert Gas Store under inert gas
Condition to Avoid Hygroscopic,Heat Sensitive
CAS RN 159989-65-8
Related CAS RN 159989-64-7
Reaxys Registry Number 7407090
PubChem Substance ID 354333524
Merck Index (14) 6443
MDL Number

MFCD00931436

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 97.0 area%
Specific rotation [a]20/D -111 to -116 deg(C=1, MeOH)(calcd.on anh.substance)
Water 2.0 to 8.0 %
Properties (reference)
Specific Rotation -112° (C=1,MeOH)
GHS
Hazard Statements H413 : May cause long lasting harmful effects to aquatic life.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P273 : Avoid release to the environment.
Related Laws:
RTECS# NW6995333
Transport Information:
HS Number 2933499090
Application
ヒト免疫不全ウイルス (HIV) プロテアーゼ阻害剤,ネルフィナビルメシル酸塩

Nelfinavir mesylate (AG1343) is a selective inhibitor of the human immunodeficiency virus (HIV) protease which is the enzyme responsible for post-translational processing of HIV propeptides. Inhibition of the viral protease prevents cleavage of the gag and gag-pol polyprotein resulting in the production of immature, non-infectious virus. Nelfinavir in combination with nucleoside reverse transcriptase inhibitors (NRTIs), nucleotide reverse transcriptase inhibitors (NtRTIs), non-nucleoside reverse transcriptase inhibitors (NNRTIs) and/or other protease inhibitors profoundly suppresses HIV replication, and helps to increase the number of white blood cells called CD4 (T) cells which help fight off other infections. (The product is for research purpose only.)
Related compounds (NRTIs): Zidovudine [A2052], Lamivudine [L0217], Zalcitabine [D3581], Stavudine [D3580], Didanosine [D3066], Abacavir [A2694], Emtricitabine [E1007]; (NtRTIs): Tenofovir [T3006]; (NNRTIs): Efavirenz [E0997], Nevirapine [N0922].

References


PubMed Literature


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