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CAS RN: 1553-56-6 | Product Number: O0500
3-Oxo-5β-cholanoic Acid
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Purity: >95.0%(GC)(T)
Synonyms:
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 250MG |
£144.00
|
2 | 8 |
|
| 1G |
£474.00
|
1 | 7 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | O0500 |
| Purity / Analysis Method | >95.0%(GC)(T) |
| Molecular Formula / Molecular Weight | C__2__4H__3__8O__3 = 374.57 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 1553-56-6 |
| PubChem Substance ID | 354335344 |
| MDL Number | MFCD00046265 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 95.0 % |
| Purity(Neutralization titration) | min. 95.0 % |
| Specific rotation [a]20/D | +31.0 to +35.0 deg(C=1, CHCL3) |
Properties (reference)
| Specific Rotation | 32° (C=1,CHCl3) |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
| RTECS# | FZ2281400 |
Transport Information:
| HS Number | 2918300090 |
Application
リトコール酸の主代謝生成物，3-オキソ-5β-コラン酸 (3-ケトコラン酸)
3-Oxo-5β-cholanoic acid (3-ketocholanoic acid) is the major human hepatic cytochrome P 450 3A (CYP3A) metabolite of lithocholic acid [L0089] which is a monohydroxy secondary bile acid and a hepatotoxic and carcinogenic bile acid. (The product is for research purpose only.)
References
- 3-Ketocholanoic acid is the major in vitro human hepatic microsomal metabolite of lithocholic acid
- An ultra-high performance liquid chromatography-tandem mass spectrometric assay for quantifying 3-ketocholanoic acid: Application to the human liver microsomal CYP3A-dependent lithocholic acid 3-oxidation assay
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