text.skipToContent text.skipToNavigation

Maximum quantity allowed is 999

Please select the quantity

CAS RN: 95-54-5 | Product Number: P0168

1,2-Phenylenediamine


Purity: >98.0%(GC)(T)
Synonyms:
  • 1,2-Diaminobenzene
Documents:
25G
£12.00
7   ≥20 
100G
£25.00
4   ≥20 
500G
£73.00
4   ≥20 

*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).


Product Number P0168
Purity / Analysis Method >98.0%(GC)(T)
Molecular Formula / Molecular Weight C__6H__8N__2 = 108.14  
Physical State (20 deg.C) Solid
Store Under Inert Gas Store under inert gas
Condition to Avoid Light Sensitive,Air Sensitive
CAS RN 95-54-5
Reaxys Registry Number 606074
PubChem Substance ID 87574418
SDBS (AIST Spectral DB) 2795
Merck Index (14) 7284
Colour Index 76010
MDL Number

MFCD00007721

Specifications
Appearance White to Light yellow to Dark green powder to crystal
Purity(GC) min. 98.0 %
Purity(Nonaqueous Titration) min. 98.0 %
Melting point 100.0 to 105.0 °C
Properties (reference)
Melting Point 103 °C
Boiling Point 265 °C
Solubility in water Soluble
Degree of solubility in water 41 g/l   35 °C
Solubility (very soluble in) Alcohol,Chloroform,Ether
Solubility (soluble in) Acetone,Benzene
GHS
Pictogram Pictogram Pictogram Pictogram
Signal Word Danger
Hazard Statements H330 : Fatal if inhaled.
H301 : Toxic if swallowed.
H312 : Harmful in contact with skin.
H319 : Causes serious eye irritation.
H371 : May cause damage to organs.
H370 : Causes damage to organs.
H373 : May cause damage to organs through prolonged or repeated exposure.
H317 : May cause an allergic skin reaction.
H341 : Suspected of causing genetic defects.
H351 : Suspected of causing cancer.
H410 : Very toxic to aquatic life with long lasting effects.
Precautionary Statements P273 : Avoid release to the environment.
P260 : Do not breathe dust/ fume/ gas/ mist/ vapours/ spray.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P391 : Collect spillage.
P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor.
P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth.
P304 + P340 + P310 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor.
P403 + P233 : Store in a well-ventilated place. Keep container tightly closed.
Related Laws:
EC Number 202-430-6
RTECS# SS7875000
Transport Information:
UN Number UN1673
Class 6.1
Packing Group III
HS Number 2921511910
Application
One-pot Synthesis of Benzodiazepin Derivatives via Three-component Reaction

P0168

References


Application
Synthesis of Benzimidazole Using Gold’s Reagent

A dry, three-necked, round-bottomed flask is equipped with a condenser, thermometer, magnetic stirrer and is placed under a nitrogen atmosphere. Into the flask is placed 100 mL of dry 1,4-dioxane along with 5.4 g (0.05 mol) of 1,2-phenylenediamine and 9.9 g (0.061 mol) of Gold’s reagent. The mixture is refluxed overnight, cooled to room temperature and 4.1 g (0.05 mol) of anhydrous sodium acetate and 2 mL of glacial acetic acid are added. The resulting mixture is refluxed for 3 hours, cooled to room temperature and the solvent is removed in vacuo. The residue is taken up in chloroform (100 mL), extracted with a saturated, aqueous solution of sodium bicarbonate (3 x 50 mL) and dried over anhydrous magnesium sulfate. After removing the drying agent by filtration, the chloroform extract is concentrated in vacuo to leave a solid which is collected by vacuum filtration with the aid of a small amount (15 mL) of water. The resulting benzimidazole amounts to 3.7 g (63% yield).

References


PubMed Literature


Articles/Brochures

TCIMAIL
Documents
Safety Data Sheet (SDS) Search
Please select Language.

The requested SDS is not available.

• Please check that the Product Number you have entered is correct.

• If your information is correct and you are still not able to view the requested SDS,  please Contact Us for more information.

C of A & Other Certificates
Please enter Lot Number Incorrect Lot Number is entered
Other Documents