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CAS RN: 94-62-2 | Product Number: P0460

Piperine


Purity: >97.0%(HPLC)(N)
Synonyms:
  • 1-[5-(1,3-Benzodioxol-5-yl)-2,4-pentadienoyl]piperidine
  • 1-Piperoylpiperidine
  • 1-Piperylpiperidine
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1G
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5G
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Product Number P0460
Purity / Analysis Method >97.0%(HPLC)(N)
Molecular Formula / Molecular Weight C__1__7H__1__9NO__3 = 285.34  
Physical State (20 deg.C) Solid
CAS RN 94-62-2
Reaxys Registry Number 90741
PubChem Substance ID 87574654
SDBS (AIST Spectral DB) 11113
Merck Index (14) 7472
MDL Number

MFCD00005839

Specifications
Appearance White to Light yellow to Light orange powder to crystal
Purity(HPLC) min. 97.0 area%
Purity(with Total Nitrogen) min. 97.0 %
Melting point 128.0 to 133.0 °C
Properties (reference)
Melting Point 129 °C
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H302 : Harmful if swallowed.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
Related Laws:
EC Number 202-348-0
RTECS# TN2321500
Transport Information:
HS Number 2939790090
Application
Piperine: A Natural Piperidine Alkaloid with TRPV1 Activation Ability

Piperine is a natural piperidine alkaloid responsible for the pungency of black pepper. It has been used as a traditional medicine for the treatment of various diseases. The pungency results from activation of the heat- and acidity-sensing TRPV1 ion channels, also known as the capsaicin receptor.1,2) In addition, piperine inhibits P-glycoprotein and/or CYP3A4 which are responsible for the metabolism and transport of xenobiotics and metabolites in the body.3,4) Therefore, piperine has potential to increase bioavailability of other compounds in food and dietary supplements, such as curcumin [C0434][C2302].4,5) (The product is for research purpose only.)

References


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