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CAS RN: 481-42-5 | Product Number: P1139

Plumbagin


Purity: >98.0%(T)(HPLC)
Synonyms:
  • 5-Hydroxy-2-methyl-1,4-naphthoquinone
Documents:
1G
£136.00
1   15  

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Product Number P1139
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__1H__8O__3 = 188.18 
Physical State (20 deg.C) Solid
CAS RN 481-42-5
Reaxys Registry Number 1870475
PubChem Substance ID 87575243
Merck Index (14) 7538
MDL Number

MFCD00001682

Specifications
Appearance Orange to Brown powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 98.0 %
Melting point 76.0 to 79.0 °C
Solubility in hot Methanol very faint turbidity
Properties (reference)
Melting Point 77 °C
GHS
Pictogram Pictogram Pictogram
Signal Word Danger
Hazard Statements H301 : Toxic if swallowed.
H314 : Causes severe skin burns and eye damage.
Precautionary Statements P260 : Do not breathe dust or mist.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P303 + P361 + P353 : IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water.
P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth.
P304 + P340 + P310 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor.
P305 + P351 + P338 + P310 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor.
Related Laws:
EC Number 207-569-6
RTECS# QL8500000
Transport Information:
UN Number UN2923
Class 8 / 6.1
Packing Group III
HS Number 2914698090
Application
Efflux pump inhibitor

In vitro analysis revealed the ability of plumbagin to increase susceptibility to several antibiotics through the inhibition of AcrB-mediated substrate efflux.1)

References


Application
Plumbagin: A Plant Secondary Metabolite with Many Biological Activities

Plumbagin is one of the plant secondary metabolite of three major phylogenic families, Plumbaginaceae, Droseraceae, and Ebenaceae. Pharmacological studies indicate that plumbagin exhibits many biological activities, such as antitumor, antibacterial, antifungal, anti-inflammatory and antioxidant activities. (The product is for research purpose only.)

References


PubMed Literature


Documents (Note: Some products will not have analytical charts available.)
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