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CAS RN: 103177-37-3 | Product Number: P2115

Pranlukast


Purity: >98.0%(HPLC)
Synonyms:
Documents:
25MG
£27.00
2   25  
100MG
£88.00
1   ≥100 

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Product Number P2115
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__2__7H__2__3N__5O__4 = 481.51 
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Condition to Avoid Heat Sensitive
CAS RN 103177-37-3
Reaxys Registry Number 6548353
PubChem Substance ID 253661988
Merck Index (14) 7710
MDL Number

MFCD00864631

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Elemental analysis(Nitrogen) 14.00 to 15.00 %
Properties (reference)
Melting Point 233 °C
Solubility in water Insoluble
Solubility (soluble in) Dimethylformamide
Solubility (insoluble in) Ethanol
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
H413 : May cause long lasting harmful effects to aquatic life.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P273 : Avoid release to the environment.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ eye protection/ face protection.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P332 + P313 : If skin irritation occurs: Get medical advice/ attention.
Related Laws:
RTECS# CV5647500
Transport Information:
HS Number 2934999090
Application
Pranlukast: A Cysteinyl Leukotriene (Cys-LT) Receptor Antagonist

Pranlukast (ONO-1078) is a selective and competitive antagonist of the cysteinyl leukotriene receptor (Cys-LTR). Cysteinyl leukotrienes (Cys-LTs) LTC4, LTD4 and LTE4 are potent proinflammatory mediators derived from arachidonic acid [A0781] through the 5-lypoxigenase (5-LO) pathway. Cys-LTs induce pathophysiological responses such as potent bronchoconstriction, mucus secretion, mucosal edema, vascular hyperpermeability and eosinophil infiltration. Hence, Cys-LTs are important mediators of allergy and inflammation. (The product is for research purpose only.)

References


PubMed Literature


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