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CAS RN: 36791-04-5 | Product Number: R0077

Ribavirin


Purity: >98.0%(HPLC)(N)
Synonyms:
  • 1-(β-D-Ribofuranosyl)-1,2,4-triazole-3-carboxamide
Documents:
100MG
£12.00
2   ≥20 
500MG
£40.00
3   ≥20 

*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).


Note:

This product is a sample for RUO (research use only). Do not use this product for any purpose other than testing and research.

Product Number R0077
Purity / Analysis Method >98.0%(HPLC)(N)
Molecular Formula / Molecular Weight C__8H__1__2N__4O__5 = 244.21  
Physical State (20 deg.C) Solid
CAS RN 36791-04-5
Reaxys Registry Number 892462
PubChem Substance ID 87559671
Merck Index (14) 8198
MDL Number

MFCD00058564

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(with Total Nitrogen) min. 98.0 %
Specific rotation [a]20/D -33.0 to -37.0 deg(C=1, H2O)
Properties (reference)
Specific Rotation -36° (C=1,H2O)
Solubility in water Soluble
Degree of solubility in water 142 g/l   25 °C
Solubility (slightly sol. in) Alcohol
GHS
Pictogram Pictogram
Signal Word Danger
Hazard Statements H360 : May damage fertility or the unborn child.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P405 : Store locked up.
Related Laws:
RTECS# XZ4250000
Transport Information:
HS Number 2934999090
Application
Ribavirin: A Ribonucleoside Analog with Antiviral Activity

Ribavirin, a ribonucleoside analog, shows antiviral activity against a variety of viruses both in vitro and in vivo. Although its mechanism of action remains unknown exactly, five distinct mechanisms have been proposed to explain the antiviral properties of ribavirin. These include both direct mechanisms (interference with RNA capping, RNA polymerase inhibition, lethal mutagenesis) and indirect mechanisms (inosine monophosphate dehydrogenase inhibition, immunomodulatory effects). Ribavirin is widely used in combination with interferon-α (IFN-α) to treat hepatitis C virus infection. The addition of ribavirin greatly improves IFN-α responses. (The product is for research purpose only.)

References


PubMed Literature


TCIMAIL
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