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CAS RN: 106266-06-2 | Product Number: R0087

Risperidone


Purity: >98.0%(T)(HPLC)
Synonyms:
  • 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
Documents:
50MG
£12.00
1   ≥20 
500MG
£35.00
7   18  

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Product Number R0087
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__2__3H__2__7FN__4O__2 = 410.49  
Physical State (20 deg.C) Solid
CAS RN 106266-06-2
Reaxys Registry Number 4891881
PubChem Substance ID 125307687
Merck Index (14) 8233
MDL Number

MFCD00274576

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Melting point 170.0 to 174.0 °C
Properties (reference)
Melting Point 172 °C
GHS
Pictogram Pictogram
Signal Word Danger
Hazard Statements H301 : Toxic if swallowed.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth.
P405 : Store locked up.
Related Laws:
RTECS# UV1164800
Transport Information:
UN Number UN2811
Class 6.1
Packing Group III
HS Number 2934999090
Application
Risperidone: A Dopamine D2 and Serotonin 5-HT2 Receptors Antagonist

Risperidone, a benzisoxazole derivative, acts as a dopamine type 2 (D2) and serotonin type 2 (5-HT2) receptors antagonist. In addition, risperidone has affinity for α1- and α2-adrenergic, and H1 histaminergic receptors. While, risperidone has low to moderate affinity for the serotonin 5-HT1C, 5-HT1D and 5-HT1A receptors, week affinity for the dopamine D1 and haloperidol-sensitive sigma binding site, and no affinity for cholinergic muscarinic or β1 and β2 adrenergic receptors. Its major active metabolite is paliperidone (9-hydroxyrisperidone) [P1897]. Risperidone is used as a long acting antipsychotic agent with relatively few side effects. (The product is for research purpose only.)

References


Application
HDAC2 may be a New Target for Schizophrenia Treatment

References


PubMed Literature


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