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CAS RN: 128-13-2 | Product Number: U0030

Ursodeoxycholic Acid


Purity: >98.0%(T)
Synonyms:
  • 5β-Cholanic Acid-3α,7β-diol
  • 3α,7β-Dihydroxy-5β-cholanic Acid
Documents:
5G
£43.00
3   ≥40 
25G
£159.00
3   ≥40 

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Product Number U0030
Purity / Analysis Method >98.0%(T)
Molecular Formula / Molecular Weight C__2__4H__4__0O__4 = 392.58 
Physical State (20 deg.C) Solid
CAS RN 128-13-2
Reaxys Registry Number 3219888
PubChem Substance ID 87577760
SDBS (AIST Spectral DB) 11242
Merck Index (14) 9889
MDL Number

MFCD00003680

Specifications
Appearance White to Almost white powder to crystaline
Purity(Neutralization titration) min. 98.0 %(after drying)
Melting point 200.0 to 205.0 °C
Specific rotation [a]20/D + 59.0 to + 62.0 deg(C=4, EtOH)
Solubility in EtOH almost transparency
Drying loss max. 1.0 %
Properties (reference)
Melting Point 203 °C
Specific Rotation 60.5° (C=4,EtOH)
Solubility in water Insoluble
Degree of solubility in water 20 mg/l   20 °C
Solubility (slightly sol. in) Chloroform
GHS
Related Laws:
EC Number 204-879-3
RTECS# FZ2000000
Transport Information:
HS Number 2918199890
Application
Synthesis of Biaryls

Ursodeoxycholic acid (ursodiol or UDCA) is a main active compound of bile bear which has been widely used in traditional Chinese medicine for the purpose of promoting the flow of bile (choleretic effect). It is a secondary bile acid resulting from bacterial actions in the colon, and is normally present as a minor fraction of the total bile acids in humans. However, it alters bile acid composition, resulting in decreases in the concentration of the more hydrophobic and cytotoxic bile acids. Furthermore, some studies have suggested that ursodeoxycholic acid protects hepatocytes against bile acid-induced apoptosis. Recently, ursodeoxycholic acid is increasingly used for the treatment of cholestatic liver diseases. (The product is for research purpose only.)

References


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