text.skipToContent text.skipToNavigation

Maximum quantity allowed is 999

Please select the quantity

CAS RN: 137862-53-4 | Product Number: V0112

Valsartan


Purity: >98.0%(T)(HPLC)
Synonyms:
  • N-Valeryl-N-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-L-valine
Documents:
1G
£22.00
2   ≥20 
5G
£74.00
2   ≥20 

*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).


Product Number V0112
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__2__4H__2__9N__5O__3 = 435.53  
Physical State (20 deg.C) Solid
CAS RN 137862-53-4
Reaxys Registry Number 7754038
PubChem Substance ID 125307697
SDBS (AIST Spectral DB) 52923
Merck Index (14) 9916
MDL Number

MFCD00865840

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 98.0 %
Specific rotation [a]20/D -63.0 to -67.0 deg(C=1, methanol)
Properties (reference)
Melting Point 117 °C
Specific Rotation -65° (C=1,MeOH)
Solubility (soluble in) Methanol
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H361 : Suspected of damaging fertility or the unborn child.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P405 : Store locked up.
Related Laws:
RTECS# YV9455000
Transport Information:
HS Number 2933998090
Application
Valsartan: A Competitive and Selective AT1 Receptor Antagonist

Valsartan is a competitive and selective AT1 receptor antagonist. Valsartan inhibits the actions of angiotensin II at the AT1 receptor subtype which is responsible for most of the known effects of angiotensin II, a principal pressor agent. Angiotensin II is formed from angiotensin I in a reaction catalyzed by angiotensin-converting enzyme (ACE). Valsartan blocks the binding of angiotensin II to the AT1 receptor in many tissues, such as vascular smooth muscle. Recently, the combination of valsartan and a thiazide diuretic hydrochlorothiazide [H1274] is often use in clinical. (The product is for research purpose only.)

References


PubMed Literature


Documents
Safety Data Sheet (SDS)
Please select Language.

The requested SDS is not available.

Please Contact Us for more information.

Specifications
C of A & Other Certificates
Please enter Lot Number Incorrect Lot Number is entered
Analytical Charts
Please enter Lot Number Incorrect Lot Number is entered

The requested Analytical Chart is not available.

Other Documents