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CAS RN: 2068-78-2 | Product Number: V0129

Vincristine Sulfate


Purity: >95.0%(HPLC)
Synonyms:
  • VCR
  • Leurocristine Sulfate
  • 22-Oxovincaleukoblastine Sulfate
Documents:
25MG
£168.00
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100MG
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Product Number V0129
Purity / Analysis Method >95.0%(HPLC)
Molecular Formula / Molecular Weight C__4__6H__5__6N__4O__1__0·H__2SO__4 = 923.04 
Physical State (20 deg.C) Solid
Storage Temperature Frozen (-20°C)
Store Under Inert Gas Store under inert gas
Condition to Avoid Hygroscopic,Heat Sensitive
CAS RN 2068-78-2
Reaxys Registry Number 8047628
PubChem Substance ID 468593101
Merck Index (14) 9986
MDL Number

MFCD08706469

Specifications
Appearance White to Light yellow powder to crystaline
Purity(HPLC) min. 95.0 area%
Specific rotation [a]20/D +24.0 to +32.0 deg(C=2, H2O,calcd.on dried substance)
Drying loss max. 15.0 %
NMR confirm to structure
Properties (reference)
Melting Point 300 °C
Maximum Absorption Wavelength 293(MeOH) nm
GHS
Pictogram Pictogram Pictogram
Signal Word Danger
Hazard Statements H300 : Fatal if swallowed.
H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
H361 : Suspected of damaging fertility or the unborn child.
H341 : Suspected of causing genetic defects.
Precautionary Statements P201 : Obtain special instructions before use.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth.
Related Laws:
EC Number 218-190-0
RTECS# OH6340000
Transport Information:
UN Number UN2811
Class 6.1
Packing Group II
HS Number 2939799090
Application
Vincristine Sulfate: An Antitumor Vinca Alkaloid

Vincristine Sulfate is an antitumor vinca alkaloid obtained from a common flowering herb, the periwinkle plant (Vinca rosea Linn). The exact mechanism of action has not been determined, but vincristine sulfate has been related to the inhibition of microtubule formation in mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage. Vincristine has been reported to have neurotoxic side effects. However, the liposome encapsulation of vincristine enhances the efficacy of the vincristine antitumor activity while simultaneously decreasing the neurotoxicity associated with it. (The product is for research purpose only.)

References


Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
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