text.skipToContent text.skipToNavigation

Maximum quantity allowed is 999

Please select the quantity

CAS RN: 298-81-7 | Product Number: X0009

Xanthotoxin


Purity: >98.0%(GC)
Synonyms:
  • Methoxsalen
  • 8-Methoxypsoralen
Documents:
100MG
£14.00
1   4  
1G
£30.00
2   ≥40 

*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).


Product Number X0009
Purity / Analysis Method >98.0%(GC)
Molecular Formula / Molecular Weight C__1__2H__8O__4 = 216.19 
Physical State (20 deg.C) Solid
CAS RN 298-81-7
Reaxys Registry Number 196453
PubChem Substance ID 87577878
SDBS (AIST Spectral DB) 10625
Merck Index (14) 5988
MDL Number

MFCD00005009

Specifications
Appearance White to Orange to Green powder to crystal
Purity(GC) min. 98.0 %
Melting point 145.0 to 149.0 °C
Properties (reference)
Melting Point 147 °C
Solubility in water Insoluble
Solubility (very soluble in) Chloroform
Solubility (soluble in) Acetone
GHS
Pictogram Pictogram Pictogram
Signal Word Danger
Hazard Statements H302 : Harmful if swallowed.
H371 : May cause damage to organs.
H373 : May cause damage to organs through prolonged or repeated exposure.
H341 : Suspected of causing genetic defects.
H350 : May cause cancer.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P260 : Do not breathe dust/ fume/ gas/ mist/ vapours/ spray.
P201 : Obtain special instructions before use.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor.
Related Laws:
EC Number 206-066-9
RTECS# LV1400000
Transport Information:
HS Number 2932990090
Application
8-Methoxypsoralen (8-MOP): A Photosensitizer in Combination with UV-A irradiation, called PUVA

5-Methoxypsoralen (5-MOP) [B2840], 8-methoxypsoralen (8-MOP) and 4,5',8-trimethylpsoralen [T2267] are naturally occurring linear psoralens (furocoumarins). They have been successfully used as photosensitizers in combination with UV-A irradiation which is called the psoralen-based PUVA (psoralen + UV-A) to manage dermatological diseases, such as psoriasis, vitiligo and cancer. Reportedly, the most important mechanism implies the [2+2] cycloaddition photoreaction of psoralen and a DNA pyrimidine nucleobase. The formation of psoralen-pyrimidine adducts prevents the division of the injured cells. In another photoreaction, the activated psoralen can transfer energy to molecular oxygen to generate reactive radicals or excited singlet oxygen which becomes prone to damage the membrane of the harmed cell. In addition, 5-MOP and 8-MOP work as Cytochrome P450 inhibitors. (The product is for research purpose only.)

References


PubMed Literature


TCIMAIL
Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.

The requested SDS is not available.

Please Contact Us for more information.

Specifications
C of A & Other Certificates
Please enter Lot Number Incorrect Lot Number is entered
Analytical Charts
Please enter Lot Number Incorrect Lot Number is entered

The requested analytical chart is not available. Sorry for the inconvenience.

Other Documents