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CAS RN: 68291-97-4 | Product Number: Z0026

Zonisamide


Purity: >98.0%(HPLC)(N)
Synonyms:
  • 1,2-Benzisoxazole-3-methanesulfonamide
Documents:
200MG
£23.00
3   9  
1G
£81.00
6   ≥20 

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Product Number Z0026
Purity / Analysis Method >98.0%(HPLC)(N)
Molecular Formula / Molecular Weight C__8H__8N__2O__3S = 212.22  
Physical State (20 deg.C) Solid
CAS RN 68291-97-4
Reaxys Registry Number 1077076
PubChem Substance ID 253659643
Merck Index (14) 10192
MDL Number

MFCD00865316

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(with Total Nitrogen) min. 98.0 %
Melting point 163.0 to 167.0 °C
Properties (reference)
Melting Point 165 °C
GHS
Pictogram Pictogram Pictogram
Signal Word Warning
Hazard Statements H302 : Harmful if swallowed.
H361 : Suspected of damaging fertility or the unborn child.
H336 : May cause drowsiness or dizziness.
Precautionary Statements P261 : Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray.
P201 : Obtain special instructions before use.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P304 + P340 + P312 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell.
Related Laws: / Compliance with laws, Regulations
RTECS# DE4930000
Transport Information:
HS Number 2935909099
Application
Studies of the Antiepileptic Action of Zonisamide
References

Carbonic anhydrase inhibitors. Zonisamide is an effective inhibitor of the cytosolic isozyme II and mitochondrial

G. De Simone, A. Di Fiore, V. Menchise, C. Pedone, J. Antel, A. Casini, A. Scozzafava, M. Wurl, C. T. Supuran, Bioorg. Med. Chem. Lett. 2005, 15, 2315.

Zonisamide blocks T-type calcium channel in cultured neurons of rat cerebral cortex

S. Suzuki, K. Kawakami, S. Nishimura, Y. Watanabe, K. Yagi, M. Scino, K. Miyamoto, Epilepsy Res. 1992, 12, 21.

Effects of zonisamide on dopaminergic system

M. Okada, S. Kaneko, T. Hirano, K. Mizuno, T. Kondo, K. Otani, Y. Fukushima, Epilepsy Res. 1995, 22, 193.

The clinical pharmacokinetics of the newer antiepileptic drugs: Focus on topiramate, zonisamide and tiagabine

E. Perucca, M. Bialer, Clin. Pharmacokinet. 1996, 31, 29.

Therapeutic drug monitoring of the newer antiepileptic drugs

S. I. Johannessen, D. Battino, D. J. Berry, M. Bialer, G. Krämer, T. Tomson, P. N. Patsalos, Ther. Drug Monit. 2003, 25, 347.


PubMed Literature


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