text.skipToContent text.skipToNavigation

Maximum quantity allowed is 999

Please select the quantity

Boron-Mediated Aldol Reaction

Boron-mediated Aldol reaction proceeds by reacting boron triflate with carbonyl compounds to form a complex. The complex is deprotonated at α-position by amine to form an enolate. Boron triflate derivative 1 possesses bulky cyclohexyl groups. Therefore, when triethylamine is added, anti-selective aldol adducts are obtained, whereas syn-selective aldol adducts gets produced upon addition of ethyldiisopropylamine. Abiko and corworkers have found that the reaction between propionate esters bonded with chiral auxiliaries and isobutyraldehyde in the presence of 1 and triethylamine forms high anti-selectivitie Aldol adducts with diastereoselectivities.1)


The prices are subject to change without notice. Please confirm the newest price by our online catalog before placing an order.
In addition, sales products changes with areas. Please understand that a product is not available when the product details page is not displayed.