Maintenance Notice (5:30 - 10:30 PM June 28, 2025): This website is scheduled to be unavailable due to maintenance. We appreciate your patience and understanding
Published TCIMAIL newest issue No.198
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 138982-67-9 | Product Number: Z0032
Ziprasidone Hydrochloride Monohydrate
×
![]()
×
Purity: >98.0%(HPLC)
Synonyms:
- 5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one Hydrochloride Monohydrate
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 50MG |
€27.00
|
Contact Us | 12 |
|
| 250MG |
€85.00
|
1 | 9 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | Z0032 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__1H__2__1ClN__4OS·HCl·H__2O = 467.41 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive |
| Packaging and Container | 250MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 138982-67-9 |
| Related CAS RN | 122883-93-6&146939-27-7 |
| Reaxys Registry Number | 13262593 |
| PubChem Substance ID | 253661772 |
| Merck Index (14) | 10171 |
| MDL Number | MFCD00921885 |
Specifications
| Appearance | White to Orange to Green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 97.0 % |
| Water | 3.7 to 5.0 % |
| NMR | confirm to structure |
Properties (reference)
GHS
Related Laws:
| RTECS# | NM3241200 |
Transport Information:
| HS Number | 2934208090 |
Application
Ziprasidone: A Selective Antagonist at the Dopamine D2, Serotonin 5HT2A, and 5HT1D Receptors
Ziprasidone hydrochloride monohydrate is a benzisothiazolyl piperazine-type atypical antipsychotic that shares the serotonin2A/dopamine2 (5-HT2A/D2) profile of the atypical antipsychotics. Ziprasidone functioned as a selective antagonist at the D2, 5HT2A, and 5HT1D receptors, and also as an agonist at the 5HT1A receptor. Ziprasidone is hepatically metabolized by aldehyde oxidase and cytochrome P450 3A4 (CYP3A4). (The product is for research purpose only.)
References
- Ziprasidone (CP-88,059): a new antipsychotic with combined dopamine and serotonin receptor antagonist activity
- 5-HT1A receptor activation contributes to ziprasidone-induced dopamine release in the rat prefrontal cortex
- Ziprasidone: a novel antipsychotic agent with a unique human receptor binding profile
- Ziprasidone Metabolism, Aldehyde Oxidase, and Clinical Implications (a review)
- Development and validation of a rapid RP-HPLC method for the estimation of Ziprasidone Hydrochloride Monohydrate in bulk and its capsule dosage forms
PubMed Literature
Product Articles
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.