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CAS RN: 139264-17-8 | Product Number: Z0024

Zolmitriptan


Purity: >98.0%(T)(HPLC)
Synonyms:
  • (S)-4-[[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]methyl]-2-oxazolidinone
Documents:
200MG
€23.00
1   16  
1G
€88.00
3   6  

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Product Number Z0024
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__6H__2__1N__3O__2 = 287.36  
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Condition to Avoid Heat Sensitive
CAS RN 139264-17-8
Reaxys Registry Number 7415010
PubChem Substance ID 253659590
Merck Index (14) 10189
MDL Number

MFCD00871503

Specifications
Properties (reference)
Melting Point 138 °C
Specific Rotation -4° (C=1,MeOH)
Maximum Absorption Wavelength 225 nm
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H302 : Harmful if swallowed.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
Related Laws: / Compliance with laws, Regulations
RTECS# RQ2707000
Transport Information:
HS Number 2934999090
Application
Zolmitriptan: A Selective 5-HT1B/1D Receptor Agonist

Zolmitriptan is a selective 5-HT1B/1D receptor agonist, belongs to triptans. Zolmitriptan binds with high affinity to 5-HT1 receptor subtypes (5-HT1B, 5-HT1D), and moderate affinity for a serotonergic receptor subtype (5-HT1A). Zolmitriptan is mainly metabolized by CYP1A2 to an initial metabolite N-desmethylzolmitriptan which also has high affinity for 5-HT1B/1D and moderate affinity for 5-HT1A receptors. Animal studies shows that zolmitriptan presumably exerts its therapeutic effects in the treatment of migraine headache through agonist effects at the 5-HT1B/1D receptors on intracranial blood vessels and sensory nerves of the trigeminal system. (The product is for research purpose only.)

References


PubMed Literature


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