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CAS RN: 202189-78-4 | Product Number: B5392

Bilastine


Purity: >98.0%(T)(HPLC)
Synonyms:
  • 2-[4-[2-[4-[1-(2-Ethoxyethyl)-1H-benzo[d]imidazol-2-yl]piperidin-1-yl]ethyl]phenyl]-2-methylpropanoic Acid
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250MG
250,00 €
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1G
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Product Number B5392
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__2__8H__3__7N__3O__3 = 463.62  
Physical State (20 deg.C) Solid
CAS RN 202189-78-4
Reaxys Registry Number 13851185
PubChem Substance ID 354335500
MDL Number

MFCD09837814

Specifications
Appearance White to Light yellow powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 98.0 %
Melting point 200.0 to 204.0 °C
Properties (reference)
Melting Point 202 °C
Solubility in water Insoluble
Solubility (very slightly) Ethanol
Solubility (insoluble in) Methanol
GHS
Related Laws:
Transport Information:
HS Number 2933998090
Application
Bilastine: A Selective Histamine H1 Receptor Antagonist

Bilastine is a selective histamine H1 receptor antagonist. On the other hand, the results of studies on bilastine confirmed the lack of significant antagonism against not only histamine H2 and H3 receptors but also serotonin, bradykinin, leukotriene D4, calcium, muscarinic M3-receptors, α1-adrenoceptors, and β2-adrenoceptors. Furthermore, bilastine do not cause sedation or interact with cytochrome P 450. Therefore, bilastine is used as a second generation H1-antihistamine for the treatment of allergic rhinitis and chronic urticarial. (The product is for research purpose only.)

References


PubMed Literature


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