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CAS RN: 1229-29-4 | Product Number: D4626

Doxepin Hydrochloride (mixture of isomers)

Purity: >98.0%(T)(HPLC)
  • 11-(3-Dimethylaminopropylidene)-6,11-dihydrodibenzo[b,e]oxepine Hydrochloride (mixture of isomers)
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Product Number D4626
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__9H__2__1NO·HCl = 315.84  
Physical State (20 deg.C) Solid
CAS RN 1229-29-4
Related CAS RN 1668-19-5
Reaxys Registry Number 5463221
PubChem Substance ID 253662533
Merck Index (14) 3435
MDL Number


Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 %(total of isomers)
Purity(Nonaqueous Titration) min. 98.0 %
Melting point 186.0 to 190.0 °C
Properties (reference)
Melting Point 188 °C
Maximum Absorption Wavelength 298 nm
Pictogram Pictogram
Signal Word Danger
Hazard Statements H301 : Toxic if swallowed.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth.
P405 : Store locked up.
Related Laws:
RTECS# HQ4375000
Transport Information:
UN Number UN2811
Class 6.1
Packing Group III
HS Number 2932990090
Doxepin Hydrochloride: A Monoamine Reuptake Inhibitor with a Wide Range of Pharmacological Properties

Doxepin hydrochloride has a wide range of pharmacological properties including an antinoradrenergic property. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H1 and H2 receptors. Doxepin hydrochloride is a family of tricyclic antidepressant agents such as amitriptyline hydrochloride [A0908] and imipramine hydrochloride. (The product is for research purpose only.)


PubMed Literature

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