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CAS RN: 29216-28-2 | Product Number: M2807


Purity: >98.0%(GC)(T)
  • 10-(Quinuclidin-3-ylmethyl)-10H-phenothiazine
  • 10-(1-Azabicyclo[2.2.2]oct-3-ylmethyl)-10H-phenothiazine
2   5  
3   ≥20 

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Product Number M2807
Purity / Analysis Method >98.0%(GC)(T)
Molecular Formula / Molecular Weight C__2__0H__2__2N__2S = 322.47  
Physical State (20 deg.C) Solid
Condition to Avoid Light Sensitive
CAS RN 29216-28-2
Reaxys Registry Number 1150945
PubChem Substance ID 354333324
Merck Index (14) 5864
MDL Number


Appearance White to Almost white powder to crystal
Purity(GC) min. 98.0 %
Purity(Nonaqueous Titration) min. 98.0 %
Melting point 146.0 to 150.0 °C
Properties (reference)
Melting Point 148 °C
Solubility in water Insoluble
Solubility (very soluble in) Methanol
Solubility (soluble in) Ethanol
Pictogram Pictogram
Signal Word Danger
Hazard Statements H301 : Toxic if swallowed.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth.
P405 : Store locked up.
Related Laws:
EC Number 249-521-7
RTECS# SP5080000
Transport Information:
UN Number UN2811
Class 6.1
Packing Group III
HS Number 2934309090

Mequitazine is a long-acting and selective histamine H1-receptor antagonist. Mequitazine also possesses antagonistic activity for leukotrienes (LTs) and platelet activating factor (PAF). In the inhibition process, mequitazine acts to inhibit the Ca2+ release from intracellular calcium store of mast cells. Mequitazine is mainly biotransformed by cytochrome P450 2D6 (CYP2D6) in human liver to yield aromatic hydroxylated and S-oxidized metabolites.


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