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CAS RN: 54-71-7 | Product Number: P0434

Pilocarpine Hydrochloride


Purity: >98.0%(T)(HPLC)
Synonyms:
  • 3-Ethyl-4-[(1-methyl-5-imidazolyl)methyl]tetrahydrofuran-2-one Hydrochloride
Documents:
1G
€26.00
6   ≥20 
5G
€104.00
3   ≥20 

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Product Number P0434
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__1H__1__6N__2O__2·HCl = 244.72  
Physical State (20 deg.C) Solid
Condition to Avoid Light Sensitive
CAS RN 54-71-7
Reaxys Registry Number 4034491
PubChem Substance ID 87574632
Merck Index (14) 7424
MDL Number

MFCD00012722

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Melting point 201.0 to 205.0 °C
Specific rotation [a]20/D +89.0 to +94.0 deg(C=2, H2O)
Solubility in Water almost transparency
Properties (reference)
Melting Point 203 °C
Specific Rotation 92° (C=2,H2O)
Solubility in water Completely soluble
Solubility (very soluble in) Alcohol
Solubility (insoluble in) Ether,Chloroform
GHS
Pictogram Pictogram
Signal Word Danger
Hazard Statements H300 + H330 : Fatal if swallowed or if inhaled.
Precautionary Statements P260 : Do not breathe dust/ fume/ gas/ mist/ vapours/ spray.
P264 : Wash skin thoroughly after handling.
P284 : Wear respiratory protection.
P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth.
P304 + P340 + P310 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor.
P403 + P233 : Store in a well-ventilated place. Keep container tightly closed.
Related Laws:
EC Number 200-212-5
RTECS# TK1450000
Transport Information:
UN Number UN1544
Class 6.1
Packing Group III
HS Number 2939800000
Application
Pilocarpine Hydrochloride: A Muscarinic Acetylcholine Receptor Agonist

Pilocarpine is an imidazole alkaloid contained in the leaves of Pilocarpus jaborandi and Pilocarpus microphyllus distributed throughout South America. It is a direct acting cholinergic parasympathomimetic agent which acts through direct stimulation of muscarinic acetylcholine receptors (M1, M2, and M3) with low affinity for nicotine receptors. In clinical, formulations of pilocarpine hydrochloride have been used for the treatment of elevated intraocular pressure and dry mouth. (The product is for research purpose only.)

References


PubMed Literature


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