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CAS RN: 483-14-7 | Product Number: T3311

L-Tetrahydropalmatine


Purity: >98.0%(HPLC)
Synonyms:
  • (13aS)-2,3,9,10-Tetramethoxy-5,8,13,13a-tetrahydro-6H-dibenzo[a,g]quinolizine
Documents:
250MG
€67.00
2   ≥20 

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Product Number T3311
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__2__1H__2__5NO__4 = 355.43  
Physical State (20 deg.C) Solid
CAS RN 483-14-7
Reaxys Registry Number 96288
PubChem Substance ID 253661327
MDL Number

MFCD03265591

Specifications
Appearance White to Light yellow powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 96.0 %
Melting point 140.0 to 144.0 °C
Specific rotation [a]20/D -278.0 to -298.0 deg(C=1, EtOH)
Properties (reference)
Melting Point 142 °C
Specific Rotation -283° (C=1,EtOH)
Maximum Absorption Wavelength 280 nm
GHS
Related Laws:
RTECS# HQ1792500
Transport Information:
HS Number 2933998090
Application
A Plant Alkaloid Effective in Multidrug Resistant Cancer Cells

L-Tetrahydropalmatine (L-THP or l-THP), the active enantiomer of THP [T3650], is an alkaloid found in several plant species such as Corydalis and Stephania. Corydalis Tuber (Corydalis yanhusuo) containing L-THP has been used for traditional Chinese pain medicine. Since L-THP antagonizes dopamine D1/D2 receptors and acts on dopamine D3 receptors, as well as α-adrenergic and serotonin receptors, it may have utility for treating opioid addiction.1,2) Furthermore, it has been reported that L-THP shows activity against antineoplastic resistant cancer cells.3) (The product is for research purpose only.)

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