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CAS RN: 67-97-0 | Product Number: C0314

Cholecalciferol


Purity: >98.0%(HPLC)
Synonyms:
  • 7-Dehydrocholesterol, activated
  • Vitamin D3
Documents:
1G
$49.00
≥100  25  

* Please contact our distributors or TCI to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.


Product Number C0314
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__2__7H__4__4O = 384.65 
Physical State (20 deg.C) Solid
Storage Temperature Frozen (<0°C)
Store Under Inert Gas Store under inert gas
Condition to Avoid Air Sensitive,Heat Sensitive
Packaging and Container 1G-Glass Bottle with Plastic Insert (View image)
CAS RN 67-97-0
PubChem Substance ID 125308742
SDBS (AIST Spectral DB) 10003
Merck Index (14) 10019
MDL Number

MFCD00078131

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Specific rotation [a]20/D +103 to +112 deg(C=0.5, EtOH)
Absorbance 0.450 to 0.510(10mg/L, EtOH, 263.0 to 267.0 nm)
NMR confirm to structure
Properties (reference)
Melting Point 86 °C
Specific Rotation 108° (C=0.5,EtOH)
Solubility in water Insoluble
Solubility (soluble in) Alcohol, Chloroform
GHS
Pictogram Pictogram Pictogram
Signal Word Danger
Hazard Statements H300 + H310 + H330 : Fatal if swallowed, in contact with skin or if inhaled.
H360 : May damage fertility or the unborn child.
H372 : Causes damage to organs through prolonged or repeated exposure.
H413 : May cause long lasting harmful effects to aquatic life.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P273 : Avoid release to the environment.
P260 : Do not breathe dust/ fume/ gas/ mist/ vapors/ spray.
P270 : Do not eat, drink or smoke when using this product.
P262 : Do not get in eyes, on skin, or on clothing.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P271 : Use only outdoors or in a well-ventilated area.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P284 : Wear respiratory protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P361 + P364 : Take off immediately all contaminated clothing and wash it before reuse.
P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth.
P302 + P352 + P310 : IF ON SKIN: Wash with plenty of water. Immediately call a POISON CENTER/doctor.
P304 + P340 + P310 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor.
P403 + P233 : Store in a well-ventilated place. Keep container tightly closed.
P405 : Store locked up.
Related Laws:
RTECS# VS2900000
Transport Information:
UN Number UN2811
Class 6.1
Packing Group II
H.S.code* 2936.29-000
*This code is applied to the products when TCI exports from Japan and not for import in your country.
Application
Efflux pump inhibitor

References


Application
Cholecalciferol (Vitamin D3): A Compound for the Maintenance of Normal Skeleton Architecture and Mineral Homeostasis

Cholecalciferol (Vitamin D3) is known for the maintenance of normal skeleton architecture and mineral homeostasis. Vitamin D3 is synthesized from 7-dehydrocholesterol [CAS: 434-16-2] in the skin under the influence of UV light, or it is obtained from food, especially fatty fish. The transformation (hydroxylation) of vitamin D3 is catalyzed by enzymes in the liver and the kidney to produce calcitriol [C3078] (other name: 1α,25-dihydroxyvitamin D3), the active form of vitamin D3. Calcitriol is active in the regulation of the absorption of calcium from the gastrointestinal tract. (The product is for research purpose only.)

References


PubMed Literature


TCIMAIL
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