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CAS RN: 1206711-16-1 | Product Number: D5737
DMH-1
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Purity: >98.0%(HPLC)
Synonyms:
- 4-[6-(4-Isopropoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 10MG |
$182.00
|
18 | 0 | It can be shipped in about 2 weeks after ordering | |
| 50MG |
$664.00
|
1 | 19 | It can be shipped in about 2 weeks after ordering |
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to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.
| Product Number | D5737 |
Purity / Analysis Method 
|
>98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__4H__2__0N__4O = 380.45 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Hygroscopic,Heat Sensitive |
| Packaging and Container
|
10MG-Glass Bottle with Plastic Insert (View image), 50MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 1206711-16-1 |
| Reaxys Registry Number | 20934957 |
| PubChem Substance ID | 468591528 |
| MDL Number | MFCD18384963 |
Specifications
| Appearance | White to Orange to Green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Melting point | 176.0 to 180.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 178 °C |
GHS
Related Laws:
| RTECS# | VC0620000 |
Transport Information:
| H.S.code* | 2933.59-000 |
Application
DMH-1: A Selective Bone Morphogenetic Protein (BMP) Receptor Inhibitor
DMH1 is a selective bone morphogenetic protein (BMP) receptor inhibitor. BMP plays a fundamental role in the regulation of bone organogenesis through the activation of receptor serine/threonine kinases, and BMP signaling regulates many different biological processes, including cell growth, differentiation, and embryogenesis. DMH1 inhibits the BMP signaling.
References
- DMH1, a Highly Selective Small Molecule BMP Inhibitor Promotes Neurogenesis of hiPSCs: Comparison of PAX6 and SOX1 Expression during Neural Induction
- DMH1, a novel BMP small molecule inhibitor, increases cardiomyocyte progenitors and promotes cardiac differentiation in mouse embryonic stem cells
- Small molecule inhibitor of the bone morphogenetic protein pathway DMH1 reduces ovarian cancer cell growth
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