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CAS RN: 30562-34-6 | Product Number: G0334
Geldanamycin
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Purity: >95.0%(qNMR)
Synonyms:
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 10MG |
$290.00
|
3 | 22 | It can be shipped in about 2 weeks after ordering |
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| Product Number | G0334 |
Purity / Analysis Method 
|
>95.0%(qNMR) |
| Molecular Formula / Molecular Weight | C__2__9H__4__0N__2O__9 = 560.64 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Frozen (<0°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container
|
10MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 30562-34-6 |
| Reaxys Registry Number | 6835113 |
| PubChem Substance ID | 87560649 |
| MDL Number | MFCD00274570 |
Specifications
| Appearance | White to Yellow to Orange powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(qNMR) | min. 95.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 255 °C |
| Maximum Absorption Wavelength | 305 nm (MeOH) |
| Solubility (soluble in) | Methanol, Ethanol, Chloroform |
| Solubility (slightly sol. in) | Acetone, Benzene |
GHS
Related Laws:
| RTECS# | LX8920000 |
Transport Information:
| H.S.code* | 2924.29-000 |
Application
Studies on Geldanamycin as a Heat Shock Protein 90 (Hsp90) Inhibitor
References
- Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent
- Structural Basis for Inhibition of the Hsp90 Molecular Chaperone by the Antitumor Antibiotics Radicicol and Geldanamycin
- Geldanamycin as a potential anticancer agent: Its molecular target and biochemical activity
- HSP90 as a new therapeutic target for cancer therapy: the story unfolds
- Hsp90 inhibitor geldanamycin and its derivatives as novel cancer chemotherapeutic agents
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