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CAS RN: 26864-56-2 | Product Number: P2076
Penfluridol
 
									 
							Purity: >98.0%(T)
Synonyms:
						
						- 1-[4,4-Bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]-4-piperidinol
Product Documents:
                    
				
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| Product Number | P2076 | 
| Purity / Analysis Method   | >98.0%(T) | 
| Molecular Formula / Molecular Weight | C__2__8H__2__7ClF__5NO = 523.97 | 
| Physical State (20 deg.C) | Solid | 
| Storage Temperature   | Refrigerated (0-10°C) | 
| Condition to Avoid | Heat Sensitive | 
| Packaging and Container   | 1G-Glass Bottle with Plastic Insert (View image), 200MG-Glass Bottle with Plastic Insert (View image) | 
| CAS RN | 26864-56-2 | 
| Reaxys Registry Number | 1558826 | 
| PubChem Substance ID | 253660023 | 
| Merck Index (14) | 7087 | 
| MDL Number | MFCD00866714 | 
Specifications
		  | Appearance | White to Almost white powder to crystal | 
| Purity(HPLC) | min. 96.0 area% | 
| Purity(Nonaqueous Titration) | min. 98.0 % | 
| Melting point | 106.0 to 110.0 °C | 
| NMR | confirm to structure | 
		Properties (reference)
	| Melting Point | 108 °C | 
 
						 GHS
						 | Pictogram |   | 
| Signal Word | Danger | 
| Hazard Statements | H301 : Toxic if swallowed. | 
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. | 
 
								 Related Laws: 
							   | RTECS# | TN6957000 | 
 
						Transport Information:
							| UN Number | UN2811 | 
| Class | 6.1 | 
| Packing Group | III | 
| H.S.code* | 2933.39-000 | 
			Application
		
			Studies of the Antipsychotic Properties of a Diphenylbutylpiperdine Derivative, Penfluridol
		
		References
- Antischizophrenic drugs of the diphenylbutylpiperidine type act as calcium channel antagonists
- Preferential block of T-type calcium channels by neuroleptics in neural crest-derived rat and human C cell lines- J. J. Enyeart, B. A. Biagi, B. Mlinar, Mol. Pharmacol. 1992, 42, 364.
 
- Maitotoxin-elicited calcium influx in cultured cells. Effect of calcium-channel blockers
- β-Subunit coexpression and the α1 subunit domain I-II linker affect piperidine block of neuronal calcium channels- G. W. Zamponi, T. W. Soong, E. Bourinet, T. P. Snutch, J. Neurosci. 1996, 16, 2430.
 
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