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CAS RN: 480-66-0 | Product Number: T1888
2',4',6'-Trihydroxyacetophenone Monohydrate
 
									 
							Purity: >98.0%(GC)
Synonyms:
						
						- 2-Acetylphloroglucinol Monohydrate
- Phloroacetophenone Monohydrate
- THAP Monohydrate
Product Documents:
                    
				| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time | Shipping Information   | 
|---|---|---|---|---|---|
| 5G | 
                                                $45.00 | 7 | ≥100 | Contact Us | |
| 25G | 
                                                $130.00 | 0 | ≥80 | Contact Us | 
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						* The storage conditions are subject to change without notice.
| Product Number | T1888 | 
| Purity / Analysis Method   | >98.0%(GC) | 
| Molecular Formula / Molecular Weight | C__8H__8O__4·H__2O = 186.17 | 
| Physical State (20 deg.C) | Solid | 
| Storage Temperature   | Room Temperature (Recommended in a cool and dark place, <15°C) | 
| CAS RN | 480-66-0 | 
| Reaxys Registry Number | 1911197 | 
| PubChem Substance ID | 87577604 | 
| MDL Number | MFCD00002287 | 
Specifications
		  | Appearance | Light orange to Yellow to Green powder to crystal | 
| Purity(GC) | min. 98.0 % | 
| Melting point | 213.0 to 223.0 °C | 
| Water | 8.5 to 11.0 % | 
		Properties (reference)
	| Melting Point | 215 °C | 
 
						 GHS
						 | Pictogram |   | 
| Signal Word | Warning | 
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. | 
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. | 
 
								 Related Laws: 
							   | RTECS# | AN0528000 | 
 
						Transport Information:
							| H.S.code* | 2914.50-000 | 
			Application
		
			A Matrix for MALDI TOF Mass Spectrometry
		
		Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry is a standard soft ionization technique in mass spectrometry. 2',4',6'-Trihydroxyacetophenone (THAP) is often used as a matrix for MALDI-TOF mass spectrometry, for nucleotide, anthocyanin and phosphorylated peptide analysis in particular. Incidentally, IUPAC defined standard terms relating to mass spectrometry in 2013 (free access).
References
- Matrix-assisted laser desorption ionization time-of-flight mass spectrometry: A powerful tool for the mass and sequence analysis of natural and modified oligonucleotides
- The study of 2,3,4-trihydroxyacetophenone and 2,4,6-trihydroxyacetophenone as matrixes for DNA detection in matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
- Analysis of anthocyanins in red wine and fruit juice using MALDI-MS
- Enhanced ionization of phosphorylated peptides during MALDI TOF mass spectrometry
- Definitions of terms relating to mass spectrometry (IUPAC Recommendations 2013)
			PubMed Literature
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