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Advantages
- Safe, easy-to-handle and stable liquid
- A practical generator of active CF3O anion species
- Enables trifluoromethoxylation of electrophilic substrates; alkyl halides and triflates, unsaturated and aromatic compounds
- Useful for synthesis of biologically active compounds and drug discovery studies
Applications
Trifluoromethoxylation of secondary alcoholic hydroxyl groups
Trifluoromethoxylation of alkyne moiety
Related Products
References
- Trifluoromethyl Nonaflate: A Practical Trifluoromethoxylating Reagent and its Application to the Regio- and Stereoselective Synthesis of Trifluoromethoxylated Alkenes
- A Fruitful Decade of Organofluorine Chemistry: New Reagents and Reactions
