Maintenance Notice (4:00 AM November 1 - 9:30 AM November 1, 2025): This website is scheduled to be unavailable due to maintenance. We appreciate your patience and understanding.
Published TCIMAIL newest issue No.199
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 108-05-4 | Product Number: A0045
Vinyl Acetate Monomer (stabilized with HQ)
×
![]()
×
Purity: >99.0%(GC)
Synonyms:
- Acetic Acid Vinyl Ester Monomer (stabilized with HQ)
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 500ML |
€18.00
|
≥40 | ≥100 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | A0045 |
Purity / Analysis Method 
|
>99.0%(GC) |
| Molecular Formula / Molecular Weight | C__4H__6O__2 = 86.09 |
| Physical State (20 deg.C) | Liquid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Condition to Avoid | Light Sensitive,Air Sensitive |
| CAS RN | 108-05-4 |
| Reaxys Registry Number | 1209327 |
| PubChem Substance ID | 87561748 |
| SDBS (AIST Spectral DB) | 1299 |
| Merck Index (14) | 9992 |
| MDL Number | MFCD00008713 |
Specifications
| Appearance | Colorless clear liquid |
| Purity(GC) | min. 99.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | -93 °C |
| Boiling Point | 72 °C |
| Flash point | -8 °C |
| Specific Gravity (20/20) | 0.93 |
| Refractive Index | 1.40 |
| Solubility in water | Slightly soluble |
| Degree of solubility in water | 25 g/l 20 °C |
| Solubility (miscible with) | Alcohol, Ether |
| Solubility (soluble in) | Acetone, Chloroform |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H332 : Harmful if inhaled. H319 : Causes serious eye irritation. H373 : May cause damage to organs through prolonged or repeated exposure. H341 : Suspected of causing genetic defects. H351 : Suspected of causing cancer. H335 : May cause respiratory irritation. H225 : Highly flammable liquid and vapour. |
| Precautionary Statements | P260 : Do not breathe dust/ fume/ gas/ mist/ vapours/ spray. P210 : Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P233 : Keep container tightly closed. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P370 + P378 : In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish. |
Related Laws:
| EC Number | 203-545-4 |
| RTECS# | AK0875000 |
Transport Information:
| UN Number | UN1301 |
| Class | 3 |
| Packing Group | II |
| HS Number | 2915320000 |
Application
Acetylation of Alcohols via Biotransformation using Acetylating Reagents
References
- 1)Regioselective Lipase-catalyzed Acylation of 4,6-O-benzylidene-α-and-β-D-pyranoside Derivatives Displaying a Range of Anomeric Substituents
- 2)On the Regioselective Acylation of 1,6-Anhydro-β-D-and L-Hexopyranoses Catalyzed by Lipases: Structural Basis and Synthetic Applications
- 3)Regioselective Acylation of Polyhydroxylated Natural Compounds Catalyzed by Candida Antarctica Lipase B (Novozym 435) in Organic Solvents
- 4)Protection for the Hydroxyl Group, Including 1,2-and 1,3-Diols
- P. G. M. Wuts, in Greene’s Protective Groups in Organic Synthesis, 5th ed., ed. by P. G. M. Wuts, John Wiley & Sons, Inc., Hoboken, New Jersey, 2014, Chap. 2, 17.
Application
Acetylation of Alcohols via Transesterification using Acetylating Reagents
References
- 1)Acylation of Alcohols and Amines with Vinyl Acetates Catalyzed by Cp*2Sm(thf)2
- 2)Protection for the Hydroxyl Group, Including 1,2- and 1,3-Diols
- P. G. M. Wuts, in Greene’s Protective Groups in Organic Synthesis, 5th ed., ed. by P. G. M. Wuts, John Wiley & Sons, Inc., Hoboken, New Jersey, 2014, Chap. 2, 17.
Application
Acetylation of Alcohols using Acetylating Reagents and Acid Catalysts
References
- 1)Molecular Iodine Catalyzed Selective Acetylation of Alcohols with Vinyl Acetate
- 2)Molecular Iodine in Isopropenyl Acetate (IPA): A Highly Efficient Catalyst for the Acetylation of Alcohols, Amines and Phenols under Solvent Free Conditions
- 3)Protection for the Hydroxyl Group, Including 1,2- and 1,3-Diols
- P. G. M. Wuts, in Greene’s Protective Groups in Organic Synthesis, 5th ed., ed. by P. G. M. Wuts, John Wiley & Sons, Inc., Hoboken, New Jersey, 2014, Chap. 2, 17.
Application
Rhodium-Catalyzed Cross-coupling of Organoboron Compounds with Vinyl Acetate
Typical procedure: Under nitrogen atmosphere, a mixture of an arylboron compounds (0.50 mmol), [RhCl(cod)]2 (6.2 mg, 13 µmol), DPPB (11.7 mg, 28 µmol), and K3PO4 (320 mg, 1.5 mmol) is diluted with toluene (2.0 mL). Alkenyl acetate (1.1 or 2.5 mmol) and tert-amyl alcohol (0.55-1.5 mmol) are added into the resulting suspension at room temperature. The mixture is stirred at 100℃ for 24 h and then diluted with hexane (2.0 mL) or EtOAc (2.0 mL). After the filtration through a Celite pad, solvent is removed from the filtrate under reduced pressure. The residue is purified with a flash column chromatography (EtOAc-hexane) to give the desired product.
References
PubMed Literature
Documents
Product Articles
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.