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Published TCIMAIL newest issue No.198
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CAS RN: 464-92-6 | Product Number: A2475
Asiatic Acid
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Purity: >97.0%(T)
Synonyms:
- 2α,3β,23-Trihydroxy-12-ursen-28-oic Acid
- 2α,23-Dihydroxyursolic Acid
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 200MG |
€78.00
|
Contact Us | 28 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | A2475 |
Purity / Analysis Method 
|
>97.0%(T) |
| Molecular Formula / Molecular Weight | C__3__0H__4__8O__5 = 488.71 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 464-92-6 |
| PubChem Substance ID | 468590113 |
| MDL Number | MFCD00238541 |
Specifications
| Purity(HPLC) | min. 95.0 area% |
| Purity(Neutralization titration) | min. 97.0 % |
| Specific rotation [a]20/D | +47.0 to +52.0 deg(C=0.1, MeOH) |
Properties (reference)
| Melting Point | 318 °C(dec.) |
| Specific Rotation | 50.3° (C=0.25,MeOH) |
GHS
| Hazard Statements | H413 : May cause long lasting harmful effects to aquatic life. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. |
Related Laws:
| RTECS# | YU9580000 |
Transport Information:
| HS Number | 2918199890 |
Application
Asiatic Acid: A Pentacyclic Triterpene Possess Wide Pharmacological Activities
Asiatic acid is a pentacyclic triterpene extracted from Centella asiatica which is a tropical medicinal plant native to India, Sri Lanka, Madagascar, South Africa, Indonesia, and Malaysia. Asiatic acid possess wide pharmacological activities, and has been widely used in Indian traditional Ayurvedic medicine. In recent years, more and more studies have been reported about the pharmacological activities, clinical application and structure modification of asiatic acid. (The product is for research purpose only.)
References
- Asiatic acid, a triterpene, induces apoptosis and cell cycle arrest through activation of extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways in human breast cancer cells
- Asiatic acid induces apoptosis in SK-MEL-2 human melanoma cells
- Inhibition of LPS-induced NO and PGE2 production by asiatic acid via NF-κB inactivation in RAW 264.7 macrophages: Possible involvement of the IKK and MAPK pathways
- Pentacyclic triterpenoids from the medicinal herb, Centella asiatica (L.) Urban (a review)
- Centella asiatica in food and beverage applications and its potential antioxidant and neuroprotective effect (a review)
- Determination of biologically active constituents in Centella asiatica
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