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Published TCIMAIL newest issue No.198
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CAS RN: 129722-12-9 | Product Number: A2496
Aripiprazole
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Purity: >98.0%(T)(HPLC)
Synonyms:
- 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 1G |
€76.00
|
1 | 15 |
|
| 5G |
€244.00
|
1 | ≥100 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | A2496 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__3H__2__7Cl__2N__3O__2 = 448.39 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 129722-12-9 |
| Reaxys Registry Number | 7951706 |
| PubChem Substance ID | 160871264 |
| Merck Index (14) | 785 |
| MDL Number | MFCD00892072 |
Specifications
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
Properties (reference)
| Melting Point | 149 °C |
| Solubility in water | Insoluble |
| Degree of solubility in water | 0.045 mg/l 25 °C |
| Solubility (insoluble in) | Methanol |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. H413 : May cause long lasting harmful effects to aquatic life. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| RTECS# | VC8275950 |
Transport Information:
| HS Number | 2933599590 |
Application
Aripiprazole: A Partial Agonist at Dopamine D2 and Serotonin 5-HT1A Receptors
Aripiprazole is a partial agonist at dopamine D2 and serotonin 5-HT1A receptors, and is an antagonist at 5-HT2A receptors. Aripiprazole is a third-generation antipsychotic agent indicated for use in the treatment of schizophrenia. Although the exact mechanism is unknown, the partial agonism and antagonism are believed to be the functional basis of its therapeutic efficacy. (The product is for research purpose only.)
References
- Aripiprazole, a novel antipsychotic, is a high-affinity partial agonist at human dopamine D2 receptors
- Aripiprazole, a novel atypical antipsychotic drug with a unique and robust pharmacology
- The antipsychotic aripiprazole is a potent, partial agonist at the human 5-HT1A receptor
- Interactions of the novel antipsychotic aripiprazole (OPC-14597) with dopamine and serotonin receptor subtypes
- Aripiprazole: a comprehensive review of its pharmacology, clinical efficacy, and tolerability (a review)
- Aripiprazole (a review on the analytical methods)
PubMed Literature
Product Articles
Product Documents (Note: Some products will not have analytical charts available.)
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