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CAS RN: 151060-21-8 | Product Number: B4354

Balofloxacin Dihydrate

Chemical Structure of Balofloxacin Dihydrate
×
× Balofloxacin Dihydrate

Purity: >98.0%(T)(HPLC)
Synonyms:
  • 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[3-(methylamino)-1-piperidyl]-4-oxoquinoline-3-carboxylic Acid Dihydrate
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5G
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Product Number B4354
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__2__0H__2__4FN__3O__4·2H__2O = 425.46 
Physical State (20 deg.C) Solid
Storage Temperature Room Temperature (Recommended in a cool and dark place, <15°C)
CAS RN 151060-21-8
Related CAS RN 127294-70-6
Reaxys Registry Number 8362117
PubChem Substance ID 253661053
MDL Number

MFCD00864925
Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 98.0 %(as Dihydrate)
Water 6.5 to 10.5 %
Properties (reference)
Melting Point 135 °C
GHS
Related Laws:
RTECS# VB1993755
Transport Information:
HS Number 2933491090
Application
Balofloxacin: An 8-Methoxyfluoroquinolone Antibiotic

Balofloxacin (Q-35) is a fluoroquinolone antibiotic, in which a OMe group is substituted at the 8 position of the quinoline nucleus. In vitro, it has a broad spectrum of activity against Gram-positive bacteria (eg. Mycoplasma pneumoniae and Staphylococcus aureus including MRSA) which is almost equal to that of sparfloxacin [S0896] or tosufloxacin [T2506]. In contrast, its activity against Gram-negative bacteria is lower. In animal studies, balofloxacin do not exhibit any phototoxicity which is a toxicity of fluoroquinolone antibiotic, in general.

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