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CAS RN: 1153949-11-1 | Product Number: B5217
1-(tert-Butoxycarbonyl)-3-(cyanomethylene)azetidine
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Purity: >95.0%(GC)
Synonyms:
- 1-Boc-3-(cyanomethylene)azetidine
- tert-Butyl 3-(Cyanomethylene)azetidine-1-carboxylate
- 3-(Cyanomethylene)azetidine-1-carboxylic Acid tert-Butyl Ester
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 200MG |
€26.00
|
1 | 28 |
|
| 1G |
€88.00
|
1 | 24 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | B5217 |
Purity / Analysis Method 
|
>95.0%(GC) |
| Molecular Formula / Molecular Weight | C__1__0H__1__4N__2O__2 = 194.23 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| CAS RN | 1153949-11-1 |
| Reaxys Registry Number | 19197759 |
| PubChem Substance ID | 354334411 |
| MDL Number | MFCD12761241 |
Specifications
| Appearance | White to Orange to Green powder to crystal |
| Purity(GC) | min. 95.0 % |
| Melting point | 89.0 to 93.0 °C |
Properties (reference)
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 + H311 + H331 : Toxic if swallowed, in contact with skin or if inhaled. H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P261 : Avoid breathing dust. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P302 + P352 + P312 : IF ON SKIN: Wash with plenty of water. Call a POISON CENTER/doctor if you feel unwell. P403 + P233 : Store in a well-ventilated place. Keep container tightly closed. |
Related Laws:
Transport Information:
| UN Number | UN3439 |
| Class | 6.1 |
| Packing Group | III |
| HS Number | 2933998090 |
Application
A Synthetic Intermediate of Baricitinib
This product is used as a synthetic intermediate of baricitinib which is an inhibitor of janus kinase (JAK), blocking the subtypes JAK1 and JAK2, for the potential treatment of various inflammatory disorders, including rheumatoid arthritis.
References
- An efficient synthesis of baricitinib
- A green and facile synthesis of an industrially important quaternary heterocyclic intermediates for baricitinib
PubMed Literature
Product Documents (Note: Some products will not have analytical charts available.)
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