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Published TCIMAIL newest issue No.198
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CAS RN: 61-68-7 | Product Number: M1782
Mefenamic Acid
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Purity: >98.0%(T)
Synonyms:
- N-(2,3-Dimethylphenyl)anthranilic Acid
- 2-(2,3-Dimethylphenylamino)benzoic Acid
- 2-(2,3-Xylidino)benzoic Acid
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 25G |
€29.00
|
14 | 36 |
|
| 100G |
€79.00
|
2 | 4 |
|
| 500G |
€252.00
|
1 | 10 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | M1782 |
| Purity / Analysis Method | >98.0%(T) |
| Molecular Formula / Molecular Weight | C__1__5H__1__5NO__2 = 241.29 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 61-68-7 |
| Reaxys Registry Number | 2216243 |
| PubChem Substance ID | 87558870 |
| SDBS (AIST Spectral DB) | 51771 |
| Merck Index (14) | 5798 |
| MDL Number | MFCD00051721 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(Neutralization titration) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 230 °C |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H302 : Harmful if swallowed. H361 : Suspected of damaging fertility or the unborn child. H362 : May cause harm to breast-fed children. H371 : May cause damage to organs. H370 : Causes damage to organs. H372 : Causes damage to organs through prolonged or repeated exposure. |
| Precautionary Statements | P263 : Avoid contact during pregnancy and while nursing. P260 : Do not breathe dust. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor. |
Related Laws:
| EC Number | 200-513-1 |
| RTECS# | CB4550000 |
Transport Information:
| HS Number | 2922498590 |
Application
Mefenamic Acid: A Non-Selective Non-Steroidal Anti-Inflammatory Drug (NSAID)
Mefenamic acid is a non-steroidal anti-inflammatory drug (NSAID) with strong analgesic activity. It is a non-selective cyclooxygenase (COX) inhibitor. COX directs the formation of several key mediators of inflammation called prostaglandins. Thus, mefenamic acid reduces the synthesis of prostaglandins. Mefenamic acid is metabolized principally by CYP2C9. Recently, some unique biological properties of mefenamic acid have also been reported. (The product is for research purpose only.)
References
- Inhibition of prostaglandin biosynthesis
- Selective COX-2 inhibitors: a review of their structure-activity relationships (a review)
- Binding of CYP2C9 with diverse drugs and its implications for metabolic mechanism
- The potential and promise of mefenamic acid (a review)
PubMed Literature
Documents
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