Published TCIMAIL newest issue No.198
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 2398-96-1 | Product Number: T3059
Tolnaftate
×
![]()
×
Purity: >97.0%(HPLC)(N)
Synonyms:
- O-2-Naphthyl Methyl(3-methylphenyl)carbamothioate
- Methyl(3-methylphenyl)carbamothioic Acid O-2-Naphthyl Ester
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 1G |
€26.00
|
Contact Us | 19 |
|
| 5G |
€93.00
|
Contact Us | 10 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | T3059 |
| Purity / Analysis Method | >97.0%(HPLC)(N) |
| Molecular Formula / Molecular Weight | C__1__9H__1__7NOS = 307.41 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 2398-96-1 |
| Reaxys Registry Number | 2752620 |
| PubChem Substance ID | 253661582 |
| Merck Index (14) | 9519 |
| MDL Number | MFCD00056611 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Purity(with Total Nitrogen) | min. 97.0 % |
| Melting point | 111.0 to 115.0 °C |
Properties (reference)
| Melting Point | 113 °C |
| Maximum Absorption Wavelength | 258 nm (MeOH) |
| Solubility in water | Insoluble |
| Solubility (slightly sol. in) | Ether |
GHS
Related Laws:
| EC Number | 219-266-6 |
| RTECS# | FD8891300 |
Transport Information:
| HS Number | 2930909599 |
Application
Tolnaftate: A Synthetic Antifungal Reagent
Tolnaftate is a chemical synthetic antifungal reagent. Although the exact mechanism of action is not entirely known, tolnaftate would inhibit sterol biosynthesis at the level of squalene epoxidase which is an important enzyme in the biosynthetic pathway of the fungal membrane.
References
- The mode of antifungal action of tolnaftate
- Ergosterol biosynthesis inhibition by the thiocarbamate antifungal agents tolnaftate and tolciclate
- Tolnaftate (a review)
- Spectrophotometric methods for the determination of tolnaftate
- Analysis of some antifungal drugs by spectrophotometric and spectrofluorimetric methods in different pharmaceutical dosage forms
PubMed Literature
Documents
Product Articles
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.