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CAS RN: | Product Number: A2510
Anti-Lewis Y Monoclonal Antibody
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Product Documents:
| Size | Unit Price | Belgium | Japan* |
Shipping Information
|
|---|---|---|---|---|
| 1VIAL |
€297.00
|
Contact Us | 7 |
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
Supplemental Product Information:
Product Information
Volume/Quantity : 0.1 mg
Product Form : Purified mouse monoclonal antibody/IgG3, κ-chain
Buffer : Phosphate buffered-saline (PBS)
Preparation : The antibody is purified from ascites fluid.
Preservative : 0.05% Sodium azide
Stabilizer : None
Immunogen : Immunized with human gastric cancer cells (MKN74), and screened using cancer glycolipids
Specificity : Lewis Y antigen
Clone Name : H18A
Application
ELISA, Flow cytometry, Immunohistochemistry, Western blot, TLC-immunostaining.
Storage
Store at －20 ºC to －80 ºC (Preferably at －80 ºC). It is not recommended storing at 4 ºC. Avoid repeated freezing and thawing.
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| Product Number | A2510 |
| Physical State (20 deg.C) | Liquid |
Storage Temperature 
|
Frozen (-80°C) |
| Condition to Avoid | Heat Sensitive |
Specifications
| Appearance | Colorless to Almost colorless clear liquid |
| Titer(ELISA) | to pass test |
Properties (reference)
GHS
Related Laws:
Transport Information:
| HS Number | 3002150000 |
Application
Anti-Lewis Y Monoclonal Antibody
References
- High idiotypic connectivity of the VH7183-encoded antibodies directed to a murine embryonic carbohydrate antigen, Lewis Y, as ascertained by syngenic anti-idiotype monoclonal antibodies.
- K. Hirashima, K. Zenita, A. Takada, A. Kitahara, G. Ishihara, R. Harada, K. Ohmori, S. Hirohashi, S. Kyoizumi, M. Akiyama, R. Kannagi, J. Immunol. 1990, 145, 224-232.
- Preparation of mouse-human chimeric antibody to an embryonic carbohydrate antigen, Lewis Y.
- T. Kaneko, Y. Iba, K. Zenita, K. Shigeta, K. Nakano, W. Itoh, Y. Kurosawa, R. Kannagi, K. Yasukawa, J. Biochem. 1993, 113, 114-117.
- Targeted gene transfer for adenocarcinoma using a combination of tumor-specific antibody and tissue-specific promoter.
- Transgene expression of alpha(1,2)-fucosyltransferase-I (FUT1) in tumor cells selectively inhibits sialyl-Lewis x expression and binding to E-selectin without affecting synthesis of sialyl-Lewis a or binding to P-selectin.
- Lewis y antigen is expressed in oral squamous cell carcinoma cell lines and tissues, but disappears in the invasive regions leading to the enhanced malignant properties irrespective of sialyl-Lewis x.
- Reactivities of Lewis antigen monoclonal antibodies with the lipopolysaccharides of Helicobacter pylori strains isolated from patients with gastroduodenal diseases in Japan.
- K. Amano, S. Hayashi, T. Kubota, N. Fujii, S. Yokota, Clin. Diagn. Lab. Immunol. 1997, 4, 540-544.
- Developmental changes in the biochemical and immunological characters of the carbohydrate moiety of neuroglycan C, a brain-specific chondroitin sulfate proteoglycan.
- Detection of ligands for selectins in the oligosaccharide fraction of human milk.
- Expression of glycolipids bearing Lewis phenotypes in tissues and cultured cells of human gynecological cancers.
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