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Published TCIMAIL newest issue No.199
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CAS RN: 65391-42-6 | Product Number: B4000
Ubenimex Hydrochloride [for Biochemical Research]
![Chemical Structure of Ubenimex Hydrochloride [for Biochemical Research]](/medias/B4000.jpg?context=bWFzdGVyfHJvb3R8NDk1MjR8aW1hZ2UvanBlZ3xhRFkwTDJoa055ODRPVEl3TVRneU5qZzFOekkyTDBJME1EQXdMbXB3Wnd8ZGMwZGYzZTY1MzAyNzFkNmY5NDQ3MjkzYjk0YTAwNWFhMGI2YWExN2FmZjM3NjFmYzg2NGEyMmVjMjgwMzYxOA "Ubenimex Hydrochloride [for Biochemical Research]")
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Purity: >97.0%(HPLC)
Synonyms:
- N-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyryl]-L-leucine Hydrochloride
Product Documents:
| Size | Unit Price | Belgium | Japan* |
Shipping Information
|
|---|---|---|---|---|
| 25MG |
€176.00
|
Contact Us | 2 |
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | B4000 |
Purity / Analysis Method 
|
>97.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__6H__2__4N__2O__4·HCl = 344.84 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Frozen (-20°C) |
| Condition to Avoid | Light Sensitive,Heat Sensitive |
| CAS RN | 65391-42-6 |
| Related CAS RN
|
58970-76-6 |
| Reaxys Registry Number | 5840390 |
| PubChem Substance ID | 253659625 |
| MDL Number | MFCD00058004 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Elemental analysis(Nitrogen) | 7.80 to 8.40 % |
| Specific rotation [a]20/D | -12.0 to -14.0 deg(C=0.5、HCl) |
| Functionality test | to pass test |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 108 °C(dec.) |
| Specific Rotation | -13° (C=0.5,1mol/L HCl) |
GHS
Related Laws:
Transport Information:
| HS Number | 2924297099 |
Application
Aminopeptidase B Inhibitor
References
- Aminopeptidase N is a receptor for tumor-homing peptides and a target for inhibiting angiogenesis
- R. Pasqualini, E. Koivunen, R. Kain, J. Lahdenranta, M. Sakamoto, A. Stryhn, R. A. Ashmun, L. H. Shapiro, W. Arap, E. Ruoslahti, Cancer Res. 2000, 60, 722.
- Bestatin, an inhibitor of aminopeptidase B, produced by actinomycetes
- Bestatin-mediated inhibition of leucine aminopeptidase may hinder HIV infection
- Leucine aminopeptidase: bestatin inhibition and a model for enzyme-catalyzed peptide hydrolysis
- Inhibition of aminopeptidases N, A and W: A re-evaluation of the actions of bestatin and inhibitors of angiotensin converting enzyme
PubMed Literature
Documents
Product Articles
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Safety Data Sheet (SDS)
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Specifications
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