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Published TCIMAIL newest issue No.201
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CAS RN: 151-73-5 | Product Number: B4110
Betamethasone 21-Phosphate Disodium Salt
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Purity: >98.0%(T)(HPLC)
Synonyms:
Product Documents:
| Size | Unit Price | Belgium | Japan* |
Shipping Information
|
|---|---|---|---|---|
| 1G |
83,00 €
|
Contact Us | ≥60 |
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | B4110 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__2H__2__8FNa__2O__8P = 516.41 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Hygroscopic |
| CAS RN | 151-73-5 |
| Related CAS RN
|
360-63-4 |
| Reaxys Registry Number | 9684703 |
| PubChem Substance ID | 253661950 |
| Merck Index (14) | 1180 |
| MDL Number | MFCD00200361 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 %(calcd.on anh.substance) |
| Specific rotation [a]20/D | +99.0 to +105.0 deg(C=1, H2O(calcd.on anh.substance)) |
| Water | max. 10.0 % |
| NMR | confirm to structure |
Properties (reference)
| Specific Rotation | 102° (C=1,H2O) |
| Solubility in water | Slightly soluble |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| EC Number | 205-797-0 |
| RTECS# | TU4056500 |
Transport Information:
| HS Number | 2937220000 |
Application
Betamethasone 21-Phosphate Disodium Salt: A Synthetic Water-Soluble Glucocorticoid
Betamethasone 21-phosphate disodium salt is a synthetic water-soluble glucocorticoid and works as a glucocorticoid receptor agonist. It shows immunosuppressive, antiallergic, antipruritic and anti-inflammatory effects in vivo. Recently, formulation of nanoparticles with betamethasone 21-phosphate disodium salt and its release profile has been studied.
References
- Anti-inflammatory effects of betamethasone phosphate, dexamethasone phosphate and indomethacin on rabbit ocular inflammation induced by bovine serum albumin
- Prolonged anti-inflammatory action of DL-lactide/glycolide copolymer nanospheres containing betamethasone sodium phosphate for an intra-articular delivery system in antigen-induced arthritic rabbit
- Treatment of experimental arthritis with poly(D,L-lactic/glycolic acid) nanoparticles encapsulating betamethasone sodium phosphate
- Treatment of experimental arthritis with stealth-type polymeric nanoparticles encapsulating betamethasone phosphate
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