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Published TCIMAIL newest issue No.201
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CAS RN: 68401-81-0 | Product Number: C2622
Ceftizoxime
×
Purity: >98.0%(T)(HPLC)
Synonyms:
Product Documents:
| Size | Unit Price | Belgium | Japan* |
Shipping Information
|
|---|---|---|---|---|
| 1G |
€77.00
|
1 | 10 | |
| 5G |
€260.00
|
1 | 5 |
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
Supplemental Product Information:
This product has not been tested for potency and is guaranteed for chemical purity.
| Product Number | C2622 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__3H__1__3N__5O__5S__2 = 383.40 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 68401-81-0 |
| Reaxys Registry Number | 5777502 |
| PubChem Substance ID | 160870913 |
| Merck Index (14) | 1951 |
| MDL Number | MFCD00072000 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Specific rotation [a]20/D | +135.0 to +145.0 deg(C=1、0.1mol/LNaOH3mL+H2O7mL) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 227 °C(dec.) |
| Specific Rotation | 139° (C=1,0.1mol/L NaOH 3mL+H2O 7mL) |
GHS
Related Laws:
| RTECS# | XI0367375 |
Transport Information:
| HS Number | 2941900000 |
Application
Ceftizoxime: A Third Generation Semisynthetic Cephalosporin Antibiotic
Ceftizoxime is a third generation semisynthetic cephalosporin antibiotic, which is chemically synthesized form 7-amino-3-nor-3-cephalosporanic acid. It has a broad spectrum of activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria, and is generally more active against Gram-negative bacteria than the first and second generation cephalosporins.
References
- Antibacterial activity of ceftizoxime, a beta-lactamase-stable cephalosporin
- Ceftizoxime. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use
- Ceftizoxime and other third-generation cephalosporins: structure-activity relationships
- Activities of beta-lactam antibiotics against Escherichia coli strains producing extended-spectrum beta-lactamases
- Involvement of MRP4 (ABCC4) in the luminal efflux of ceftizoxime and cefazolin in the kidney
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