Maintenance Notice (4:00 AM November 1 - 9:30 AM November 1, 2025): This website is scheduled to be unavailable due to maintenance. We appreciate your patience and understanding.
Published TCIMAIL newest issue No.199
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 31251-41-9 | Product Number: C3181
8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one
![Chemical Structure of 8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one](/medias/C3181.jpg?context=bWFzdGVyfHJvb3R8NDY4Nzh8aW1hZ2UvanBlZ3xhREJqTDJoaVl5ODRPVEl3T0RFMk9EYzNOVGs0TDBNek1UZ3hMbXB3Wnd8ZWIwODRjMzM1NTcwOTliYWMwYjJmMjY1MzYyMDMyNDYyMTI1NDgxZDI3YzBlZTg5Mzc3YTAxZjQzZGIxZWZmYQ "8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one")
![Thumbnail of 8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one](/medias/C3181.jpg?context=bWFzdGVyfHJvb3R8MTQ2MzJ8aW1hZ2UvanBlZ3xhRFU0TDJnNVl5ODRPVE0wTWpNek1EYzVPRE00TDBNek1UZ3hMbXB3Wnd8ZjI4MTk0ZWIzMzY4YjhiNmY4OTM5NjRiNGVlYzU1ZmFhNzdkOTA5MGUwNWFjZjUxZjM0MDZkMWRkMzY1Zjc2Yg)
×
![]()
×
![8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one](/_ui/responsive/theme-tci/images/missing_product_zoom.jpg "8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one")
Purity: >98.0%(GC)(T)
Synonyms:
- 8-Chloro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11(6H)-one
Product Documents:
| Size | Unit Price | Belgium | Japan* |
|---|---|---|---|
| 5G |
€76.00
|
1 | 1 |
| 25G |
€243.00
|
2 | 2 |
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | C3181 |
Purity / Analysis Method 
|
>98.0%(GC)(T) |
| Molecular Formula / Molecular Weight | C__1__4H__1__0ClNO = 243.69 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Frozen (<0°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 31251-41-9 |
| Reaxys Registry Number | 1465917 |
| PubChem Substance ID | 354333387 |
| MDL Number | MFCD00800222 |
Specifications
| Appearance | White to Orange to Green powder to crystal |
| Purity(GC) | min. 98.0 % |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 103.0 to 107.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 105 °C |
| Solubility (soluble in) | Methanol |
GHS
Related Laws:
Transport Information:
| HS Number | 2933998090 |
Application
A Related Substance of Loratadine and Desloratadine
The reagent is a related substance of loratadine [L0223] and desloratadine [D3787] which are histamine receptor antagonists.
References
- Hydroxylated metabolites of loratadine: an example of conformational diastereomers due to atropisomerism
- LC determination of loratadine and related impurities
- Capillary electrophoresis determination of loratadine and related impurities
- Rapid separation of desloratadine and related compounds in solid pharmaceutical formulation using gradient ion-pair chromatography
PubMed Literature
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.