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Published TCIMAIL newest issue No.201
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CAS RN: 24316-19-6 | Product Number: C3641
Cephalotaxine
×
Purity: >98.0%(GC)
Synonyms:
Product Documents:
| Size | Unit Price | Belgium | Japan* |
Shipping Information
|
|---|---|---|---|---|
| 100MG |
142,00 €
|
1 | 18 |
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | C3641 |
Purity / Analysis Method 
|
>98.0%(GC) |
| Molecular Formula / Molecular Weight | C__1__8H__2__1NO__4 = 315.37 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| CAS RN | 24316-19-6 |
| Reaxys Registry Number | 628324 |
| PubChem Substance ID | 468591206 |
| MDL Number | MFCD21090383 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(GC) | min. 98.0 % |
| Specific rotation | -91.0 to -101.0 deg(C=0.5, ethanol) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 151 °C |
| Specific Rotation | -194° (C=1,CHCl3) |
GHS
Related Laws:
Transport Information:
| HS Number | 2939799090 |
Application
Cephalotaxine: The Major Benzazepine Alkaloid of the Cephalotaxus Species.
Cephalotaxine is the major benzazepine alkaloid of the Cephalotaxus species.1) Cephalotaxine is a good target for natural product synthesis because of its unique tetracyclic ring system.2-4) Furthermore, its ester derivatives, such as harringtonine and hamoharringtonine, have been reported to act as a protein synthesis inhibitor and apoptosis inducer in tumor cells, and possess antiviral activy.5-7) (The product is for research purpose only.)
References
- 1) Alkaloids of Cephalotaxus drupaceae and Cephalotaxus fortunei
- 2) Enantioselective Highly Efficient Synthesis of (-)-Cephalotaxine Using Two Palladium-Catalyzed Transformations
- 3) A Novel and Efficient Total Synthesis of Cephalotaxine
- 4) Formal Synthesis of (-)-Cephalotaxine Based on a Tandem Hydroamination/Semipinacol Rearrangement Reaction
- 5) Antitumor alkaloids from Cephalotaxus harringtonia. Structure and activity
- 6) Harringtonine, an inhibitor of initiation of protein biosynthesis
- 7) Effect of cantharidin, cephalotaxine and homoharringtonine on "in vitro" models of hepatitis B virus (HBV) and bovine viral diarrhoea virus (BVDV) replication
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