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Published TCIMAIL newest issue No.198
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CAS RN: 130693-82-2 | Product Number: D4189
Dorzolamide Hydrochloride
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Purity: >98.0%(T)(HPLC)
Synonyms:
Product Documents:
| Size | Unit Price | Belgium | Japan* |
|---|---|---|---|
| 200MG |
€122.00
|
Contact Us | 13 |
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | D4189 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__0H__1__6N__2O__4S__3·HCl = 360.89 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 130693-82-2 |
| Related CAS RN | 120279-96-1 |
| Reaxys Registry Number | 5896026 |
| PubChem Substance ID | 160871396 |
| Merck Index (14) | 3426 |
| MDL Number | MFCD00884659 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| Specific rotation [a]20/D | -7.0 to -9.0 deg(C=1、MeOH) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 281 °C(dec.) |
| Specific Rotation | -8° (C=1,MeOH) |
| Maximum Absorption Wavelength | 254 nm (CHCl__3:MeOH= aq.) |
| Solubility in water | Soluble |
| Solubility (slightly sol. in) | Methanol |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| RTECS# | XJ9095163 |
Transport Information:
| HS Number | 2934999090 |
Application
Studies of Carbonic Anhydrase Inhibitors
References
- Pharmacological and ocular hypotensive properties of topical carbonic anhydrase inhibitors
- The preclinical pharmacology of dorzolamide hydrochloride, a topical carbonic anhydrase inhibitor
- An enantioselective synthesis of the topically-active carbonic anhydrase inhibitor MK-0507: 5,6-dihydro-(S)-4- (ethylamino)-(S)-6-methyl-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide hydrochloride
PubMed Literature
Product Articles
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Specifications
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