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Published TCIMAIL newest issue No.198
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CAS RN: 129938-20-1 | Product Number: D4761
Dapoxetine Hydrochloride
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Purity: >98.0%(HPLC)
Synonyms:
- (S)-N,N-Dimethyl-3-(1-naphthyloxy)-1-phenylpropylamine Hydrochloride
- (S)-N,N-Dimethyl-α-[2-(1-naphthyloxy)ethyl]benzylamine Hydrochloride
Product Documents:
| Size | Unit Price | Belgium | Japan* |
|---|---|---|---|
| 1G |
€61.00
|
2 | 1 |
| 5G |
€194.00
|
2 | 37 |
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | D4761 |
Purity / Analysis Method 
|
>98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__1H__2__3NO·HCl = 341.88 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 129938-20-1 |
| Reaxys Registry Number | 10603966 |
| PubChem Substance ID | 253660535 |
| Merck Index (14) | 2821 |
| MDL Number | MFCD08272809 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 97.0 % |
| Melting point | 179.0 to 183.0 °C |
| Specific rotation [a]20/D | +124 to +129 deg(C=1, MeOH) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 181 °C |
| Specific Rotation | 125° (C=1,MeOH) |
| Solubility (soluble in) | Methanol |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. H319 : Causes serious eye irritation. H413 : May cause long lasting harmful effects to aquatic life. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P280 : Wear eye protection/ face protection. P337 + P313 : If eye irritation persists: Get medical advice/ attention. |
Related Laws:
Transport Information:
| HS Number | 2922190090 |
Application
Dapoxetine Hydrochloride: A Short-Acting Selective Serotonin Reuptake Inhibitor (SSRI)
Dapoxetine hydrochloride is a short-acting selective serotonin (5-HT) reuptake inhibitor (SSRI), similar in structure to fluoxetine hydrochloride [F0750]. (The product is for research purpose only.)
References
- Dapoxetine hydrochloride (a review)
- Dapoxetine: a novel, fast-acting serotonin reuptake inhibitor (a review)
- Development and validation of a RP-HPLC method for the determination of dapoxetine hydrochloride in pharmaceutical formulation using an experimental design
- Simultaneous estimation and validation of Vardenafil and Dapoxetine Hydrochloride in pharmaceutical formulation by thin layer chromatographic densitometric method
- Determination of dapoxetine, an investigational agent with the potential for treating depression, and its mono- and di-desmethyl metabolites in human plasma using column-switching high-performance liquid chromatography
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