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CAS RN: 105601-04-5 | Product Number: D5326
3-[1-(Dimethylamino)ethyl]phenol
![Thumbnail of 3-[1-(Dimethylamino)ethyl]phenol](/medias/D5326.jpg?context=bWFzdGVyfHJvb3R8MTY3NzN8aW1hZ2UvanBlZ3xhRFZoTDJnMU9TODRPVE0wT1RNMU1qTXlOVFF5TDBRMU16STJMbXB3Wnd8ZjA2ZTlmNGQ4M2VmYTcxZjQxZTA4ZThmYTYyZDhiN2FkZjcyYzMyOGYyZjI1MGRmMWUyMmViNDVjZmZlMmE3ZA "3-[1-(Dimethylamino)ethyl]phenol")
![Chemical Structure of 3-[1-(Dimethylamino)ethyl]phenol](/medias/D5326.jpg?context=bWFzdGVyfHJvb3R8NTI1MjN8aW1hZ2UvanBlZ3xhR0U0TDJnME1pODRPVEl4TkRnd09ESXlPREUwTDBRMU16STJMbXB3Wnd8NTcyOGRhZjYwODBiMjllZGQ4MDkzOGViMWNhYjhiMTNkZWU0NmYzZDgxNmM3MGI0ODk4OTNjMjgwNWFlMWFlMg "3-[1-(Dimethylamino)ethyl]phenol")
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![3-[1-(Dimethylamino)ethyl]phenol](/_ui/responsive/theme-tci/images/missing_product_zoom.webp "3-[1-(Dimethylamino)ethyl]phenol")
Purity: >98.0%(GC)(T)
Synonyms:
Product Documents:
| Size | Unit Price | Belgium | Japan* |
Shipping Information
|
|---|---|---|---|---|
| 1G |
€16.00
|
1 | 11 | |
| 5G |
€41.00
|
Contact Us | ≥80 |
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | D5326 |
Purity / Analysis Method 
|
>98.0%(GC)(T) |
| Molecular Formula / Molecular Weight | C__1__0H__1__5NO = 165.24 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive |
| CAS RN | 105601-04-5 |
| Reaxys Registry Number | 3197913 |
| PubChem Substance ID | 468591327 |
| MDL Number | MFCD08272688 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(GC) | min. 98.0 % |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 93 °C |
| Solubility (soluble in) | Methanol |
GHS
Related Laws:
Transport Information:
| HS Number | 2922290090 |
Application
A Synthetic Intermediate of Rivastigmine L-Tartrate
This product is used for the synthesis of rivastigmine L-tartrate [R0093] which is a dual inhibitor of acetylcholinesterase (AChE) and Butyrylcholinesterase (BuChE), used for the treatment of Alzheimer’s disease.
References
- Preparation method of rivastigmine, its intermediates and preparation method of the intermediates
- F. Zhang, M. Hu, M. Xie, A. Lai, R. Sun, D. Chen, R. Bao, H. Bai, US 8324429.
- Carbamoylation method for preparation of rivastigmine [(S)-3-[(1-dimethylamino)ethyl]phenyl N-ethyl-N-methylcarbamate]
- M. M. Gharpure, B. M. Bhawal, V. B. Shah, U. R. Zope, S. R. Mehta, WO/2006/048720.
Product Documents (Note: Some products will not have analytical charts available.)
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Specifications
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