Maintenance Notice (5:30 - 10:30 PM June 28, 2025): This website is scheduled to be unavailable due to maintenance. We appreciate your patience and understanding
Published TCIMAIL newest issue No.198
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 562-10-7 | Product Number: D5583
Doxylamine Succinate
×
![]()
×
Purity: >98.0%(T)(HPLC)
Synonyms:
- N,N-Dimethyl-2-[1-phenyl-1-(pyridin-2-yl)ethoxy]ethanamine Succinate
Product Documents:
| Size | Unit Price | Belgium | Japan* |
|---|---|---|---|
| 5G |
€74.00
|
Contact Us | 6 |
| 25G |
€242.00
|
Contact Us | 16 |
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | D5583 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__7H__2__2N__2O·C__4H__6O__4 = 388.46 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Frozen (<0°C) |
| Condition to Avoid | Light Sensitive,Heat Sensitive |
| CAS RN | 562-10-7 |
| Related CAS RN
|
469-21-6 |
| PubChem Substance ID | 468591428 |
| Merck Index (14) | 3441 |
| MDL Number | MFCD00056168 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 %(total of Ion-Pair) |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 109.0 to 113.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 111 °C |
| Solubility (soluble in) | Alcohol, Chloroform |
| Solubility (slightly sol. in) | Benzene, Ether |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| EC Number | 209-228-7 |
| RTECS# | US9275000 |
Transport Information:
Application
Doxylamine Succinate: A First-Generation Anti-Histamine
Doxylamine succinate is a first-generation anti-histamine similar in structure to diphenhydramine [D4744]. Because of its sedative effect, it is often used for the treatment of insomnia and nausea in clinical use. (The product is for research purpose only.)
References
- Doxylamine succinate-pyridoxine hydrochloride (Diclegis) for the management of nausea and vomiting in pregnancy: an overview (a review)
- Simultaneous determination of pyridoxine hydrochloride and doxylamine succinate from tablets by ion pair reversed-phase high-performance liquid chromatography (RP-HPLC)
- Determination of the sleep aid ingredients diphenhydramine hydrochloride and doxylamine succinate in pharmaceutical products by quantitative HPTLC
- Simultaneous determination of dextromethorphan, dextrorphan and doxylamine in human plasma by HPLC coupled to electrospray ionization tandem mass spectrometry: Application to a pharmacokinetic study
Product Articles
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.