Published TCIMAIL newest issue No.201
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 201530-41-8 | Product Number: D5905
Deferasirox
×
Purity: >98.0%(HPLC)
Synonyms:
- 4-[3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic Acid
Product Documents:
| Size | Unit Price | Belgium | Japan* |
Shipping Information
|
|---|---|---|---|---|
| 250MG |
84,00 €
|
1 | 18 | |
| 1G |
243,00 €
|
2 | 10 |
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | D5905 |
Purity / Analysis Method 
|
>98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__1H__1__5N__3O__4 = 373.37 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image), 250MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 201530-41-8 |
| Reaxys Registry Number | 8442898 |
| PubChem Substance ID | 468591634 |
| MDL Number | MFCD09951804 |
Specifications
| Appearance | White to Gray to Brown powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 262 °C |
| Solubility in water | Insoluble |
| Degree of solubility in water | 0.02 mg/l 25 °C |
| Solubility (slightly sol. in) | Acetone |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. H413 : May cause long lasting harmful effects to aquatic life. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| RTECS# | DG4438400 |
Transport Information:
| HS Number | 2933998090 |
Application
Mitophagy research
Reference
- Iron loss triggers mitophagy through induction of mitochondrial ferritin
Application
Deferasirox: A Potent Chelating Agent with a Selective Affinity for Ferric Ion [Fe (III)]
Deferasirox (ICL670A) is a potent chelating agent with a selective affinity for ferric ion [Fe (III)]. Deferasirox binds with ferric ions to form neutral 2:1 (deferasirox:iron) complexes. And then, deferasirox has a lower binding affinity for other metals such as copper, aluminum and zinc than for iron. Deferasirox, an iron selective chelator, is used therapeutically in conditions of transfusional iron overload for the excretion of iron. (The product is for research purpose only.)
References
- ICL670A: a new synthetic oral chelator: evaluation in hypertransfused rats with selective radioiron probes of hepatocellular and reticuloendothelial iron stores and in iron-loaded rat heart cells in culture
- ICL670A: preclinical profile (a review)
- Deferasirox: a review of its use in the management of transfusional chronic iron overload
- Pharmacokinetics, distribution, metabolism, and excretion of deferasirox and its iron complex in rats
Product Documents (Note: Some products will not have analytical charts available.)
Enter TCI Product Number
Enter KISHIDA Product Number
4-5 alphanumeric characters before the hyphen
7 alphanumeric characters
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
• The requested SDS is not available.
Specifications
The requested specifications are not available.
Please Contact Us for more information.
The requested specifications are not available.
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Incorrect Lot Number. Please input only the 7 alphanumeric characters.
• Please check that the lot number you have entered is correct. It is 4-5 alphanumeric characters before the hyphen. In particular, please check O (letter) or 0 (number) and I (letter) or 1 (number).
• If your information is correct and you are still not able to view the requested certificates, Please Contact Us for more information.
• Please check that the lot number you have entered is correct. It is 7 alphanumeric characters. In particular, please check O (letter) or 0 (number) and I (letter) or 1 (number).
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Incorrect Lot Number. Please input only the 7 alphanumeric characters.
The requested analytical chart is not available. Sorry for the inconvenience.