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CAS RN: 119446-68-3 | Product Number: D6002
Difenoconazole
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Purity: >95.0%(T)(HPLC)
Synonyms:
- 1-[[2-[2-Chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1H-1,2,4-triazole
Product Documents:
| Size | Unit Price | Belgium | Japan* |
Shipping Information
|
|---|---|---|---|---|
| 5G |
€64.00
|
5 | ≥60 |
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | D6002 |
Purity / Analysis Method 
|
>95.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__9H__1__7Cl__2N__3O__3 = 406.26 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive |
| CAS RN | 119446-68-3 |
| Reaxys Registry Number | 9073356 |
| MDL Number | MFCD00144119 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(Nonaqueous Titration) | min. 95.0 % |
| Melting point | 77.0 to 82.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 78 °C |
| Solubility in water | Insoluble |
| Degree of solubility in water | 5 mg/l 20 °C |
| Solubility (soluble in) | dichloromethane, Methanol, Toluene, Acetone |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. H319 : Causes serious eye irritation. H371 : May cause damage to organs. H373 : May cause damage to organs through prolonged or repeated exposure. H351 : Suspected of causing cancer. H410 : Very toxic to aquatic life with long lasting effects. |
| Precautionary Statements | P273 : Avoid release to the environment. P260 : Do not breathe dust. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P391 : Collect spillage. |
Related Laws:
| RTECS# | XZ4380000 |
Transport Information:
| UN Number | UN3077 |
| Class | 9 |
| Packing Group | III |
| HS Number | 2934999016 |
Application
Difenoconazole: An Ergosterol Biosynthesis Inhibitor
Difenoconazole is a broad-spectrum 1,2,4-triazole fungicide that inhibits ergosterol [E0018] biosynthesis and fungal cell wall formation via inhibition of the cytochrome P450 dependent 14α-demethylation of lanosterol [C0427].1-3) Difenoconazole is used as foliage-spray or seed-treatment for the control of fungal diseases on fruits, vegetables, cereals, and other field crops. Therefore, it has been to study of the fate of difenoconazole in vegetables and soil for accurate assessment of its stress to food and environment.3-6) (The product is for research purpose only.)
References
- 1) Azole fungicides affect mammalian steroidogenesis by inhibiting sterol 14 alpha-demethylase and aromatase
- 2) In vitro sensitivity of Fusarium graminearum (Schwabe) to difenoconazole, prothioconazole and thiophanate-methyl
- 3) Chiral Triazole Fungicide Difenoconazole: Absolute Stereochemistry, Stereoselective Bioactivity, Aquatic Toxicity, and Environmental Behavior in Vegetables and Soil
- 4) Determination of difenoconazole residue in tomato during home canning by UPLC-MS/MS
- 5) Residue analysis of fipronil and difenoconazole in okra by liquid chromatography tandem mass spectrometry and their food safety evaluation
- 6) Modification of the existing maximum residue levels for difenoconazole in various crops
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